Evidence map›Paper›PMID 41340805›Full record

Trial reportActa clinica Croatica2025

EFFICACY OF NASAL IRRIGATION WITH ISOTONIC AND HYPERTONIC SOLUTIONS AFTER ENDOSCOPIC SINUS SURGERY FOR CHRONIC RHINOSINUSITIS WITH NASAL POLYPOSIS.

Ana Penezić, Livije Kalogjera, Marko Velimir Grgić, Goran Geber, Dejan Tomljenović, Konstantinos Alevizopoulos, Tomislav Baudoin

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Acta clinica Croatica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ana PenezićDepartment of Otorhinolaryngology, Head and Neck Surgery, Sestre milosrdnice University Hospital Center, Zagreb, Croatia.
Livije KalogjeraDepartment of Otorhinolaryngology, Head and Neck Surgery, Sestre milosrdnice University Hospital Center, Zagreb, Croatia.
Marko Velimir GrgićDepartment of Otorhinolaryngology, Head and Neck Surgery, Sestre milosrdnice University Hospital Center, Zagreb, Croatia.
Goran GeberDepartment of Otorhinolaryngology, Head and Neck Surgery, Sestre milosrdnice University Hospital Center, Zagreb, Croatia.
Dejan TomljenovićDepartment of Otorhinolaryngology, Head and Neck Surgery, Sestre milosrdnice University Hospital Center, Zagreb, Croatia.
Konstantinos AlevizopoulosResearch and Development Department, Gerolymatos International S.A., Athens, Greece.
Tomislav BaudoinDepartment of Otorhinolaryngology, Head and Neck Surgery, Sestre milosrdnice University Hospital Center, Zagreb, Croatia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endoscopic sinus surgery (ESS) is often involved in the treatment of patients with chronic rhinosinusitis with nasal polyposis (CRSwNP). Nasal irrigation after ESS is recommended to improve healing and nasal symptoms in these patients. This study compared the efficacy of nasal irrigation with either an isotonic solution of 0.9% NaCl or a hypertonic solution of 2.3% NaCl comprising algal extracts. This was a randomized cohort study that included patients with CRSwNP after ESS who used isotonic solution and hypertonic 2.3% solution enriched with algal extracts (

Indexed as

EndoscopyNasal LavageNasal PolypsPostoperative ComplicationsRhinosinusitisAdultChronic DiseaseFemaleHumansHypertonic SolutionsIsotonic SolutionsMaleMiddle AgedRhinitisSaline Solution, HypertonicSinusitisHypertonic SolutionsIsotonic SolutionsSaline Solution, HypertonicChronic rhi- nosinusitisEndoscopic sinus surgeryHypertonic solutionNasal irrigationNasal polyposisSeaweed extract

Identifiers

PMID41340805
PMCPMC12671714

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.