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ArticleAsian journal of neurosurgery2025

Hirayama and Granuloma-The Affinity Saga.

Sharath Kumar Goddu Govindappa, Chaitra Parameshwara Adiga, Ravi Mohan Rao Basrur, Karthikeyan Y R, Jagadish B Agadi, Lakshmikanth N Goolahally, Yashwanth S, Shilpa Rao, Abhishek Chowdhury

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In one paragraph

Article in Asian journal of neurosurgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Sharath Kumar Goddu GovindappaDepartment of Radiology, Apollo Hospitals, Seshadripuram, Bangalore, Karnataka, India.
Chaitra Parameshwara AdigaDepartment of Radiology, Apollo Hospitals, Seshadripuram, Bangalore, Karnataka, India.ORCID 0000-0002-7317-5800
Ravi Mohan Rao BasrurDepartment of Neurosurgery, Apollo Hospitals, Seshadripuram, Bangalore, Karnataka, India.
Karthikeyan Y RDepartment of Neurosurgery, Apollo Hospitals, Seshadripuram, Bangalore, Karnataka, India.
Jagadish B AgadiDepartment of Neurology, Apollo Hospitals, Seshadripuram, Bangalore, Karnataka, India.
Lakshmikanth N GoolahallyDepartment of Radiology, Apollo Hospitals, Seshadripuram, Bangalore, Karnataka, India.
Yashwanth SDepartment of Radiology, Apollo Hospitals, Seshadripuram, Bangalore, Karnataka, India.
Shilpa RaoDepartment of Neuropathology, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India.
Abhishek ChowdhuryDepartment of Neuropathology, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India.ORCID 0000-0001-7948-6936

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Foreign-body granulomas secondary to synthetic materials used in neurosurgery are common. It has been reported that most of them occur after brain surgery than spinal surgery. Hirayama disease, which presents as a slow progressive upper limb muscle weakness and subsequently atrophy, obligates surgical intervention when the conservative management fails. It is managed by posterior cervical surgery followed by dural repair, while anterior cervical surgery is also an option. The component present in duroplasty material, ReDura, may cause exuberant granuloma formation. Foreign-body granuloma at the site of dural repair secondary to the synthetic dural component can cause spinal cord compression worsening the symptoms, requiring surgery. We hereby report a case of a young male with Hirayama disease who underwent posterior cervical surgery followed by duroplasty. The mass effect by the granuloma, secondary to dural repair, was relieved surgically and patient improved neurologically.

Indexed as

granuloma formationHirayama diseaseMRI spineposterior cervical techniquesReDura

Identifiers

PMID41340764
PMCPMC12672130

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.