Evidence map›Paper›PMID 41340581›Full record

ArticleInternational endodontic journal2026

Intentional Negotiation and Filling of Accessory Canals: A Case Series With Three-Dimensional Segmentation and Volumetric Healing Assessment.

Lucas Pinto Carpena, Gabriel Lima Braz, Henrique Timm Vieira, Nadia de Souza Ferreira

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In one paragraph

Article in International endodontic journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lucas Pinto CarpenaDental School, Federal University of Pelotas-UFPel, Pelotas, Rio Grande do Sul, Brazil.ORCID https://orcid.org/0000-0002-3384-6016
Gabriel Lima BrazDental School, Federal University of Pelotas-UFPel, Pelotas, Rio Grande do Sul, Brazil.ORCID https://orcid.org/0009-0009-4858-562X
Henrique Timm VieiraDental School, Federal University of Pelotas-UFPel, Pelotas, Rio Grande do Sul, Brazil.ORCID https://orcid.org/0000-0002-0616-6007
Nadia de Souza FerreiraDental School, Federal University of Pelotas-UFPel, Pelotas, Rio Grande do Sul, Brazil.ORCID https://orcid.org/0000-0002-5123-5657

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAccessory canals (ACs) are anatomical features that may harbour residual infected tissue and contribute to persistent periradicular inflammation. Although filling of these structures is occasionally achieved passively, their intentional mechanical negotiation remains rarely documented in clinical practice. This case series aims to describe the clinical approach, outcomes and imaging strategies used in the intentional debridement and filling of ACs.

methodsSix teeth with identifiable ACs on cone-beam computed tomography (CBCT), in association with bone resorption, were included. All cases underwent chemomechanical preparation using rotary instrumentation with 2% chlorhexidine gel, active saline irrigation and final EDTA activation with passive ultrasonic irrigation. Intentional mechanical debridement of ACs was performed using small-diameter hand files. All fillings were performed with gutta-percha and AH Plus Jet sealer. Follow-up was performed using CBCT and periapical radiographs after a mean period of 10.16 months. Three-dimensional segmentation was used to aid localization and planning.

resultsAll ACs were successfully negotiated and filled with endodontic sealer. Tomographic analysis confirmed evidence of partial or complete periradicular healing in all six cases. No patients presented with clinical symptoms at follow-up.

conclusionThis case series presents successful intentional instrumentation and obturation of ACs, supported by CBCT-based planning and follow-up. Although limited by the lack of a control group, the findings highlight the potential role of CBCT imaging and segmentation in identifying and accessing complex anatomy. Further prospective studies are needed to determine the impact of this approach on long-term clinical outcomes.

Indexed as

Dental Pulp CavityImaging, Three-DimensionalRoot Canal ObturationRoot Canal PreparationAdultCone-Beam Computed TomographyFemaleGutta-PerchaHumansMaleMiddle AgedRoot Canal Filling MaterialsGutta-PerchaRoot Canal Filling Materialsaccessory canalcone beam computed tomographyroot canal anatomyroot canal treatment

Identifiers

PMID41340581
PMCPMC12977934

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.