Evidence map›Paper›PMID 41340497›Full record

ArticleArchiv der Pharmazie2025

New Se-Compounds With Antileishmanial, Antitumor, and Carbonic Anhydrase Inhibitory Properties.

Cristina Morán-Serradilla, Daniel Plano, Andrea Angelli, Arun K Sharma, Carmen Sanmartin, Claudiu T Supuran

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archiv der Pharmazie, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cristina Morán-SerradillaDepartment of Pharmaceutical Sciences, University of Navarra, Pamplona, Spain.
Daniel PlanoDepartment of Pharmaceutical Sciences, University of Navarra, Pamplona, Spain.
Andrea AngelliDepartment of NEUROFARBA, Pharmaceutical and Nutraceutical Section, University of Firenze, Florence, Italy.ORCID https://orcid.org/0000-0002-1470-7192
Arun K SharmaDepartment of Molecular and Precision Medicine, Penn State College of Medicine, Hershey, Pennsylvania, USA.
Carmen SanmartinDepartment of Pharmaceutical Sciences, University of Navarra, Pamplona, Spain.
Claudiu T SupuranDepartment of NEUROFARBA, Pharmaceutical and Nutraceutical Section, University of Firenze, Florence, Italy.ORCID https://orcid.org/0000-0003-4262-0323

Funding

Cristina Morán-Serradilla wants to acknowledge the support of the Government of Navarra for a PhD fellowship.
6 · The paper itself

Abstract

In the pursuit of novel agents for treating leishmaniasis and cancer, we have synthesized a small library of phenylcarboxamide-selenium analogs and evaluated their in vitro antileishmanial, anticancer, and carbonic anhydrase inhibitory activities. The two trifluoromethoxy-substituted aniline derivatives (3 and 6) exhibited IC

Indexed as

Antineoplastic AgentsAntiprotozoal AgentsCarbonic Anhydrase InhibitorsLeishmania majorOrganoselenium CompoundsCarbonic AnhydrasesCell Line, TumorDose-Response Relationship, DrugDrug Screening Assays, AntitumorHumansInhibitory Concentration 50Leishmania infantumMolecular StructureParasitic Sensitivity TestsStructure-Activity RelationshipAntineoplastic AgentsAntiprotozoal AgentsCarbonic Anhydrase InhibitorsCarbonic AnhydrasesOrganoselenium Compoundscancercarbonic anhydraseleishmaniasisselenium

Identifiers

PMID41340497
PMCPMC12676205

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.