Evidence map›Paper›PMID 41340208›Full record

ArticleMagnetic resonance in medicine2026

Investigation of Endogenous Renal CEST Contrast and the Influence of Respiratory Motion on a Clinical 3 Tesla MRI: An In Vivo and In Vitro Study.

Patrik Jan Gallinnis, Benedikt Kamp, Karl Ludger Radke, Rika Möller, Anna-Katharina Juric, Julia Stabinska, Vít Herynek, Gerald Antoch, Hans-Jörg Wittsack, Alexandra Ljimani and 1 more

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Patrik Jan GallinnisMedical Faculty, Department of Diagnostic and Interventional Radiology, University Dusseldorf, Dusseldorf, Germany.
Benedikt KampMedical Faculty, Department of Diagnostic and Interventional Radiology, University Dusseldorf, Dusseldorf, Germany.ORCID https://orcid.org/0000-0002-0518-5695
Karl Ludger RadkeMedical Faculty, Department of Diagnostic and Interventional Radiology, University Dusseldorf, Dusseldorf, Germany.ORCID https://orcid.org/0000-0003-1095-1283
Rika MöllerMedical Faculty, Department of Diagnostic and Interventional Radiology, University Dusseldorf, Dusseldorf, Germany.
Anna-Katharina JuricMedical Faculty, Department of Diagnostic and Interventional Radiology, University Dusseldorf, Dusseldorf, Germany.
Julia StabinskaF.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, Maryland, USA.ORCID https://orcid.org/0000-0003-2730-4250
Vít HerynekCenter for Advanced Preclinical Imaging (CAPI), First Faculty of Medicine, Charles University, Prague, Czech Republic.
Gerald AntochMedical Faculty, Department of Diagnostic and Interventional Radiology, University Dusseldorf, Dusseldorf, Germany.
Hans-Jörg WittsackMedical Faculty, Department of Diagnostic and Interventional Radiology, University Dusseldorf, Dusseldorf, Germany.ORCID https://orcid.org/0000-0002-5830-423X
Alexandra LjimaniMedical Faculty, Department of Diagnostic and Interventional Radiology, University Dusseldorf, Dusseldorf, Germany.ORCID https://orcid.org/0000-0002-9748-9927
Anja Müller-LutzMedical Faculty, Department of Diagnostic and Interventional Radiology, University Dusseldorf, Dusseldorf, Germany.

Funding

Jürgen Manchot Stiftung
6 · The paper itself

Abstract

purposeThe aim is to evaluate the effectiveness of timed breathing in reducing respiratory motion artifacts in renal chemical exchange saturation transfer (CEST) MRI and to assess potential differences in CEST effects between renal compartments.

methodsAn electro-pneumatic phantom with a kidney CEST model simulated variable respiratory motion and sequence-synchronized breathing. Motion-induced deviations from a static reference were quantified using the mean absolute error (MAE). Ten healthy volunteers (six females, four males; 25.2 ± 1.9 years) and one patient (47 years) with ccRCC (3.0 × 2.2 × 2.2) cm

resultsTimed breathing reduced motion artifacts in both phantom and in vivo data. MTR

conclusionTimed breathing improves renal CEST MRI by reducing motion artifacts and enabling detection of compartment-specific CEST effects, highlighting its potential for biochemical characterization of renal tissue in clinical applications.

Indexed as

KidneyMagnetic Resonance ImagingRespirationAdultArtifactsFemaleHealthy VolunteersHumansImage Processing, Computer-AssistedMaleMiddle AgedMotionPhantoms, Imagingabdominal CESTamide proton transferchemical exchange saturation transferdynamic phantomkidneymagnetization transfer imaging

Identifiers

PMID41340208
PMCPMC12850607

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.