Evidence map›Paper›PMID 41340118›Full record

ArticleBMC oral health2025

Alveolar bone heterogeneity during aging: a cone-beam CT based assessment of alveolar bone in tooth loss patients.

Yiwen Zhou, Jing Yang, Ke Le, Qiong Yang, Xuanxuan Yu, Jiayi He, Jie Ge, Guoyun Wang, Huang Li, Xu Yang

Abstract read
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Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Yiwen Zhou *Department of Stomatology, the First People's Hospital of Changzhou, the Third Affiliated Hospital of Soochow University, Changzhou, China.
Jing Yang *Department of Stomatology, Changzhou Hospital of Traditional Chinese Medicine, the Affiliated Hospital of Nanjing University of Chinese Medicine, Changzhou, China.
Ke LeDepartment of Stomatology, Changzhou Hospital of Traditional Chinese Medicine, the Affiliated Hospital of Nanjing University of Chinese Medicine, Changzhou, China.
Qiong YangDepartment of Stomatology, the First People's Hospital of Changzhou, the Third Affiliated Hospital of Soochow University, Changzhou, China.
Xuanxuan YuDepartment of Orthodontics, Medical School, Nanjing Stomatological Hospital, Nanjing University, Nanjing, China.
Jiayi HeDepartment of Stomatology, the First People's Hospital of Changzhou, the Third Affiliated Hospital of Soochow University, Changzhou, China.
Jie GeDepartment of Stomatology, the First People's Hospital of Changzhou, the Third Affiliated Hospital of Soochow University, Changzhou, China.
Guoyun WangDepartment of Stomatology, the First People's Hospital of Changzhou, the Third Affiliated Hospital of Soochow University, Changzhou, China.
Huang LiDepartment of Orthodontics, Medical School, Nanjing Stomatological Hospital, Nanjing University, Nanjing, China. lihuang76@nju.edu.cn.
Xu YangDepartment of Stomatology, the First People's Hospital of Changzhou, the Third Affiliated Hospital of Soochow University, Changzhou, China. czyyyangxu@163.com.

Funding

Changzhou Basic Research Program CJ20250111Changzhou Longcheng Qiangyi Doctoral Research Project KY20242212Changzhou Science and Technology Bureau CJ20220105 and CJ20245015Natural Science Research Program of Jiangsu Higher Education Institutions 25KJB320012
6 · The paper itself

Abstract

objectiveThis retrospective study aimed to evaluate differences in cortical and trabecular alveolar bone between normal dentition and edentulous sites across different age and sex groups.

methodsA total of 191 partially edentulous patients who underwent preoperative cone-beam CT (CBCT) were retrospectively analyzed. Cortical bone thickness, cortical bone density, and trabecular bone density were measured at both normal dentition and edentulous sites across six anatomical regions in the maxilla and mandible. Comparisons were made across age groups and sexes, and between paired edentulous and normal sites. Implant outcomes were recorded, and success rates were calculated.

resultsAt normal dentition sites, cortical bone thickness and density significantly declined with age, particularly in the posterior regions. Young females showed higher cortical bone mass than males, though this difference diminished with age. In contrast, trabecular bone density tended to increase with age. Edentulous sites showed significantly reduced cortical thickness, cortical density, and trabecular density compared to normal sites. Among 180 patients with implant placement, the success rate was 98.88%, with failures limited to three male patients.

conclusionThis study revealed heterogeneous alterations in alveolar bone associated with aging, with cortical bone exhibiting more pronounced atrophy than trabecular bone. Despite these variations in bone quantity and quality, implant restoration achieved a high success rate, regardless of the underlying alveolar bone condition.

Indexed as

AgingAlveolar ProcessCone-Beam Computed TomographyTooth LossAdultAgedAged, 80 and overBone DensityCortical BoneFemaleHumansMaleMiddle AgedRetrospective StudiesAgingAlveolar boneBone heterogeneityCone-beam computed tomographyCortical bone

Identifiers

PMID41340118
PMCPMC12781706

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