Evidence map›Paper›PMID 41340027›Full record

ArticleInternational journal of methods in psychiatric research2025

Developing Trace: A Transdiagnostic Screening Tool for Early Detection of a Pluripotent at-Risk Mental State.

Jayne Pickering, Wen Shao, Scott Weich, Caroline F Dalton, Myles Jones, Chris D J Taylor, Markus Reuber, Jessica Kingston, Chris Gibbs, Richard P Bentall

Abstract read
In one paragraph

Article in International journal of methods in psychiatric research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jayne PickeringUniversity of Sheffield, Sheffield, UK.ORCID 0000-0003-1105-7013
Wen ShaoUniversity of Sheffield, Sheffield, UK.
Scott WeichUniversity of Sheffield, Sheffield, UK.
Caroline F DaltonSheffield Hallam University, Sheffield, UK.
Myles JonesUniversity of Sheffield, Sheffield, UK.
Chris D J TaylorUniversity of Sheffield, Sheffield, UK.ORCID 0000-0002-1989-883X
Markus ReuberUniversity of Sheffield, Sheffield, UK.
Jessica KingstonRoyal Holloway University of London, Egham, UK.ORCID 0000-0002-1142-8083
Chris GibbsCumbria, Northumberland, Tyne and Wear NHS Foundation Trust, Newcastle Upon Tyne, UK.
Richard P BentallUniversity of Sheffield, Sheffield, UK.

Funding

University of Sheffield
6 · The paper itself

Abstract

objectivesEarly identification of individuals at risk for developing mental health disorders is critical for timely intervention, reducing distress and improving outcomes. This study outlines the development and preliminary validation of 'TRACE', a short self-report measure designed to detect a pluripotent at-risk mental state (PARMS). The measure captures a range of subthreshold symptoms and traits associated with emerging manifestations of mania, psychosis and borderline personality disorder.

methodsA sample of 2037 general-population adolescents and young adults (aged 14-36) completed TRACE questions and other psychometrics.

resultsExploratory Graph Analysis, undertaken on one-half of the dataset, generated a three-factor structure that was successfully replicated in the other half of the data, via confirmatory factor analysis. The final 26-item scale has acceptable model fit (with a scaled CFI of 0.93, TLI of 0.92, with acceptable-to-good error, RMSEA of 0.073) and good concurrent validity with other relevant psychometrics, such as neuroticism and loneliness (r = 0.29 and 0.43, respectively).

conclusionThese findings suggest that the tool may be useful in identifying individuals with a broad, pluripotent vulnerability to develop severe mental health disorders. Future research will focus on validating the tool longitudinally and across diverse populations to assess its predictive utility and clinical value.

Indexed as

Borderline Personality DisorderManiaPsychiatric Status Rating ScalesPsychometricsPsychotic DisordersAdolescentAdultEarly DiagnosisFemaleHumansMaleMental DisordersPredictive Value of TestsRisk AssessmentSelf ReportSurveys and Questionnairesat‐risk mental stateborderline personalityhypomaniapluripotentpsychosistransdiagnostic

Identifiers

PMID41340027
PMCPMC12675136

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.