Evidence map›Paper›PMID 41339998›Full record

ArticleMolecular neurobiology2025

Coenzyme Q10 Ameliorates Fibromyalgia-like Symptoms and Cognitive Deficits by Enhancing Hippocampal PGC-1α/FNDC5/BDNF Pathway in Reserpine-Treated Rats.

Muaz Belviranlı, Nilsel Okudan, Tuğba Sezer

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Muaz BelviranlıSchool of Medicine, Department of Physiology, Selçuk University, Konya, 42131, Turkey. mbelviranli@yahoo.com.ORCID http://orcid.org/0000-0002-2454-8818
Nilsel OkudanSchool of Medicine, Department of Physiology, Selçuk University, Konya, 42131, Turkey.
Tuğba SezerSchool of Medicine, Department of Physiology, Selçuk University, Konya, 42131, Turkey.

Funding

Türkiye Bilimsel ve Teknolojik Araştırma Kurumu 223S451
6 · The paper itself

Abstract

This study investigated the effects of coenzyme Q10 (CoQ10) administration on fibromyalgia (FM) symptoms and cognitive functions in a reserpine-induced FM model. It is also aimed to evaluate the role of the PGC-1α/FNDC5/BDNF pathway and oxidative stress in this process. Female Wistar rats were randomly assigned to control, FM, CoQ10, and FM + CoQ10 groups. The FM groups received daily subcutaneous reserpine (1 mg kg

Indexed as

Brain-Derived Neurotrophic FactorCognitive DysfunctionFibromyalgiaHippocampusPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaSignal TransductionUbiquinoneAnimalsAnxietyBehavior, AnimalDepressionFemaleFibronectinsHyperalgesiaOxidative StressRatsBdnf protein, ratBrain-Derived Neurotrophic Factorcoenzyme Q10FibronectinsFNDC5 protein, ratPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaPpargc1a protein, ratReserpineUbiquinoneCoenzyme Q10FibromyalgiaFNDC5Mitochondrial biogenesisReserpine

Identifiers

PMID41339998

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.