Evidence map›Paper›PMID 41339798›Full record

ArticleBMC infectious diseases2025

Genotypic spectrum and prevalence of HPV associated with cervical cancer in Palestine.

Ibrahim Salhi, Mahmoud Alzahayqa, Walaa Qrei, Tarteel Qawasmi, Mohammad Qadi, Zaidoun Salah

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PubMed Full text at PMC Publisher
In one paragraph

Article in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ibrahim SalhiClinical Laboratory Science, Department of Medical and Health Sciences, Faculty of Graduate Studies, An-Najah National University, Nablus, State of Palestine.
Mahmoud AlzahayqaMolecular Genetics Laboratories, Medicare, Ramallah, State of Palestine.
Walaa QreiMolecular Genetics Laboratories, Medicare, Ramallah, State of Palestine.
Tarteel QawasmiMolecular Genetics Laboratories, Medicare, Ramallah, State of Palestine.
Mohammad QadiDepartment of Biomedical Sciences and Basic Clinical Skills, Faculty of Medicine and Allied Medical Sciences, An-Najah National University, Nablus, State of Palestine. m.qadi@najah.edu.
Zaidoun SalahMolecular Genetics Laboratories, Medicare, Ramallah, State of Palestine. zaidouns@medicare.ps.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCervical cancer remains a significant global public health issue, primarily driven by persistent infection with Human Papillomavirus (HPV). Understanding HPV prevalence, genotype distribution, and epidemiological patterns is essential for effective cervical cancer prevention and management.

methodsThis retrospective study analysed 48 paraffin-embedded cervical tissue samples from Palestinian women diagnosed with poorly differentiated squamous cell carcinoma between 2014 and 2024. DNA extraction was successful for 40 cases. HPV detection was conducted via nested PCR targeting the HPV L1 gene, followed by genotype identification using Sanger sequencing.

resultsHPV was detected in 82.5% of samples, predominantly consisting of high-risk HPV types (77.5%), with HPV16 (32.5%) and HPV18 (10%) being the most prevalent. Women aged 50–59 years exhibited the highest HPV positivity rate. The geographical distribution showed distinct regional variations, particularly clusters of HPV16 infections in specific Palestinian regions.

conclusionsThe high prevalence of HPV, particularly high-risk genotypes such as HPV16 and HPV18, underscores the urgent need for nationwide HPV vaccination and standardized cervical cancer screening programs in Palestine. These findings provide critical epidemiological insights necessary to inform and optimize local public health strategies.

Indexed as

Human Papillomavirus VirusesPapillomaviridaePapillomavirus InfectionsUterine Cervical NeoplasmsAdultAgedCarcinoma, Squamous CellDNA, ViralFemaleGenotypeHumansMiddle AgedMiddle EastPrevalenceRetrospective StudiesDNA, ViralCervical cancerEpidemiologyHPV genotypesHPV vaccinationHuman papillomavirus (HPV)PalestinePreventionSustainable public health

Identifiers

PMID41339798
PMCPMC12781518

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