Evidence map›Paper›PMID 41339796›Full record

ArticleBMC microbiology2025

Therapeutic effect of daucosterol on DSS-induced colitis in mice.

Jing Liang, Huihui Yang, Kelin Chen, Jiahao Cai, Yuling Wang, Yanhong Yong

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jing Liang *College of Coastal Agricultural Sciences, Guangdong Ocean University, Zhanjiang, 524088, China.
Huihui Yang *College of Coastal Agricultural Sciences, Guangdong Ocean University, Zhanjiang, 524088, China.
Kelin ChenCollege of Coastal Agricultural Sciences, Guangdong Ocean University, Zhanjiang, 524088, China.
Jiahao CaiCollege of Coastal Agricultural Sciences, Guangdong Ocean University, Zhanjiang, 524088, China.
Yuling WangCollege of Coastal Agricultural Sciences, Guangdong Ocean University, Zhanjiang, 524088, China.
Yanhong YongCollege of Coastal Agricultural Sciences, Guangdong Ocean University, Zhanjiang, 524088, China. yongyanhong-007@163.com.

Funding

College Students' Innovation and Entrepreneurship Fund of Coastal Agriculture College S202410566024
6 · The paper itself

Abstract

Ulcerative colitis (UC) is an intestinal disease caused by multiple factors that severely affects the health of humans and animals. In this study, a DSS-induced mouse colitis model was utilized to investigate the ability of daucosterol (DAU) to alleviate colitis and its underlying mechanism of action. The experimental results showed that DAU could alleviate the clinical symptoms of colitis in mice, reduce the expression of proinflammatory cytokines (IL-1β, IL-6, and TNF-α) in mouse serum, and modulate the gut microbiota to alleviate DSS-induced colitis in mice. In conclusion, DAU has great potential in the prevention of colitis.

Indexed as

ColitisColitis, UlcerativeSitosterolsAnimalsCytokinesDextran SulfateDisease Models, AnimalGastrointestinal MicrobiomeInterleukin-1betaInterleukin-6MiceMice, Inbred C57BLTumor Necrosis Factor-alphaCytokinesDextran SulfateInterleukin-1betaInterleukin-6lyonisideSitosterolsTumor Necrosis Factor-alphaDaucosterolDSSGut microbiotaUlcerative colitis

Identifiers

PMID41339796
PMCPMC12781652

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.