Evidence map›Paper›PMID 41339551›Full record

ArticleNature2026

Dated gene duplications elucidate the evolutionary assembly of eukaryotes.

Christopher J Kay, Anja Spang, Gergely J Szöllősi, Davide Pisani, Tom A Williams, Philip C J Donoghue

Abstract read
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Environmental phylogenetics supports a steady diversification of crown eukaryotes starting from the mid-Proterozoic.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Review
  5. Article
  6. Divergent evolution of the PRPS enzymes across the tree of life.bioRxiv : the preprint server for biology · 2026
    Article
  7. Origin of eukaryotic plasmalogen biosynthesis by horizontal gene transfer from myxobacteria.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  8. Toward a genomic understanding of the tree of life.Molecular biology and evolution · 2026
    Article
  9. Eukaryogenesis: Did an Oxidative Crucible Result in Misleading Bioinformatic Analyses?BioEssays : news and reviews in molecular, cellular and developmental biology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Christopher J KayBristol Palaeobiology Group, School of Earth Sciences, University of Bristol, Bristol, UK. chris.kay@bristol.ac.uk.ORCID 0000-0002-4381-7438
Anja SpangDepartment of Marine Microbiology and Biogeochemistry, Royal Netherlands Institute for Sea Research (NIOZ), Den Burg, The Netherlands.ORCID 0000-0002-6518-8556
Gergely J SzöllősiMTA-ELTE "Lendulet" Evolutionary Genomics Research Group, Budapest, Hungary.ORCID 0000-0002-8556-845X
Davide PisaniBristol Palaeobiology Group, School of Biological Sciences, University of Bristol, Bristol, UK. davide.pisani@bristol.ac.uk.ORCID 0000-0003-0949-6682
Tom A WilliamsBristol Palaeobiology Group, School of Biological Sciences, University of Bristol, Bristol, UK. tom.a.williams@bristol.ac.uk.ORCID 0000-0003-1072-0223
Philip C J DonoghueBristol Palaeobiology Group, School of Earth Sciences, University of Bristol, Bristol, UK. phil.donoghue@bristol.ac.uk.ORCID 0000-0003-3116-7463

Funding

Gordon and Betty Moore FoundationLeverhulme Trust
6 · The paper itself

Abstract

The origin of eukaryotes was a formative but poorly understood event in the history of life. Current hypotheses of eukaryogenesis differ principally in the timing of mitochondrial endosymbiosis relative to the acquisition of other eukaryote novelties

Indexed as

EukaryotaEvolution, MolecularGene DuplicationArchaeaEukaryotic CellsMitochondriaPhylogenySymbiosisTime Factors

Identifiers

PMID41339551
PMCPMC12872463

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.