ArticleJournal of bone and mineral metabolism2026
Osteosarcopenia as a predictor of postoperative adverse outcomes in older adults undergoing total hip arthroplasty.
Article in Journal of bone and mineral metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Opportunistic CT assessment of psoas muscle attenuation and its association with lumbar osteoporosis in total hip arthroplasty candidates.Skeletal radiology · 2026Article
- Frailty across Hip arthroplasty pathways: vulnerability domains, outcomes, and implications for care-a narrative review.Frontiers in surgery · 2026Review
- Artificial intelligence-driven assessment of sarcopenia in orthopedic geriatrics: technical progress and clinical implications.Frontiers in endocrinology · 2026Review
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Authors and funding
5 authors.
Funding
Abstract
introductionOsteosarcopenia-the coexistence of osteoporosis and sarcopenia-reflects a dual loss of bone and muscle integrity that contributes to frailty, falls, and functional decline in aging populations. While both osteoporosis and sarcopenia have been individually linked to postoperative recovery, their combined effect after major orthopedic procedures remains unclear. This study investigated whether osteosarcopenia independently predicts health-related quality of life after total hip arthroplasty (THA), as a model for older adults with musculoskeletal deficits. MATERIALS AND
methodsA retrospective cohort of 214 patients aged ≥ 65 years who underwent unilateral THA was analyzed. Preoperative evaluations included dual-energy X-ray absorptiometry (osteoporosis: lumbar T-score < - 2.5) and sarcopenia was defined in accordance with the 2019 Asian Working Group for Sarcopenia consensus. Patients were grouped as osteosarcopenia, sarcopenia-only, osteoporosis-only, or normal. Multivariate logistic regression was conducted to identify predictors of achieving the minimum clinically important difference (MCID) in the Hip Disability and Osteoarthritis Outcome Score-Joint Replacement (HOOS-JR) at 24 months postoperatively. Propensity score matching was used to compare patients with osteosarcopenia with matched controls.
resultsBoth osteoporosis (OR 0.71, 95%CI 0.60-0.83) and sarcopenia (OR 0.79, 95%CI 0.64-0.97) were independent predictors of failure to achieve MCID (> 18, 154/214). Post-matching, patients with osteosarcopenia (n = 25) had significantly lower HOOS-JR (P < 0.001), EuroQol 5-Dimension (P = 0.029), and satisfaction scores (P < 0.001) than controls (n = 50).
conclusionOsteosarcopenia was associated with clinically inferior functional disability after THA. Preoperative identification of bone-muscle deficits could guide interventions-such as osteoporosis treatment and tailored rehabilitation-to enhance outcomes in older adults.
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Registered trials
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