Evidence map›Paper›PMID 41339524›Full record

ArticleCommunications biology2025

A comprehensive analysis of the impact of genomic imbalance on gene expression in a poplar aneuploidy population.

Yue Yu, Song Chen, Kanglei Li, Xinyu Wang, Zhijie Liu, Hanxi Li, Yuting Wang, Xuanchen Liu, Wenxuan Liu, Fuchun Li and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Communications biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yue Yu *State Key Laboratory of Tree Genetics and Breeding, Northeast Forestry University, Harbin, China.
Song Chen *State Key Laboratory of Tree Genetics and Breeding, Northeast Forestry University, Harbin, China.
Kanglei Li *State Key Laboratory of Tree Genetics and Breeding, Northeast Forestry University, Harbin, China.
Xinyu WangState Key Laboratory of Tree Genetics and Breeding, Northeast Forestry University, Harbin, China.
Zhijie LiuState Key Laboratory of Rice Biology, Key Laboratory of the Ministry of Agriculture and Rural Affairs for Nuclear-Agricultural Sciences, Zhejiang University, Hangzhou, China.
Hanxi LiState Key Laboratory of Tree Genetics and Breeding, Northeast Forestry University, Harbin, China.
Yuting WangState Key Laboratory of Tree Genetics and Breeding, Northeast Forestry University, Harbin, China.
Xuanchen LiuState Key Laboratory of Tree Genetics and Breeding, Northeast Forestry University, Harbin, China.
Wenxuan LiuState Key Laboratory of Tree Genetics and Breeding, Northeast Forestry University, Harbin, China.
Fuchun LiState Key Laboratory of Tree Genetics and Breeding, Northeast Forestry University, Harbin, China.
Quanzi LiState Key Laboratory of Tree Genetics and Breeding, Chinese Academy of Forestry, Beijing, China.
Xingguo LanState Key Laboratory of Tree Genetics and Breeding, Northeast Forestry University, Harbin, China.
Guanzheng QuState Key Laboratory of Tree Genetics and Breeding, Northeast Forestry University, Harbin, China.
Su ChenState Key Laboratory of Tree Genetics and Breeding, Northeast Forestry University, Harbin, China. chensu@nefu.edu.cn.ORCID http://orcid.org/0000-0002-8814-5444

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alteration of chromosomal dosage severely affects the expressions of cis and trans genes in human and fruit fly. However, its effect on gene expression in plants needs to be further explored. Here, we generated 84 aneuploid lines with extra 1 to 16 chromosomes by crossing a female diploid poplar and a male triploid poplar. The chromosome compositions of the aneuploid population were dissected by DNA sequencing and cytogenetics. An RNA-seq analysis showed that cis genes were affected by both dosage and inverse effects, while trans genes were mainly affected by inverse effect. When the chromosomal dosage in an aneuploid line exceeds a threshold, the inverse effect may exceed the dosage effect on cis genes, causing dosage overcompensation. Interestingly, we found that even the genes located on the same chromosome may be subjected to different types of effect. These findings provided an important theoretical basis for analyzing the gene expression from the perspective of chromosomal dosage level.

Indexed as

AneuploidyGene Expression Regulation, PlantGenome, PlantPopulusChromosomes, PlantGene Dosage

Identifiers

PMID41339524
PMCPMC12796257

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.