Evidence map›Paper›PMID 41339453›Full record

ArticleScientific reports2025

3D FusionNet for synthetic CT based lung cancer segmentation.

Chiranjib Parida, Saurabh Bilgaiyan, Santwana Sagnika, Satyabrata Roy, Ankur Pandey

Erratum issuedAbstract read
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Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Chiranjib ParidaSchool of Computer Engineering, KIIT-Deemed to be University, Bhubaneswar, 751024, Odisha, India.
Saurabh BilgaiyanSchool of Computer Engineering, KIIT-Deemed to be University, Bhubaneswar, 751024, Odisha, India.
Santwana SagnikaSchool of Computer Engineering, KIIT-Deemed to be University, Bhubaneswar, 751024, Odisha, India.
Satyabrata RoyDepartment of Computer Science and Engineering, Manipal University Jaipur, Jaipur, 303007, Rajasthan, India.
Ankur PandeyDepartment of Computer Science and Engineering, Manipal University Jaipur, Jaipur, 303007, Rajasthan, India. ankur.pandey@jaipur.manipal.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interpretation of three-dimensional medical scans continues to be a demanding task in computer-assisted diagnostic systems. In this study we present a segmentation framework specifically designed for lung CT images. Since lung cancer is one of the most fatal cancers worldwide and the demand for better detection tools remains pressing. To address this issue our proposed work combined the Deep Convolutional Generative Adversarial Networks (DCGAN) with the 3D-TDUnet++ architecture. The use of DCGAN allowed us to generate additional CT samples. Which results in reducing the problem of insufficient annotated data and improving the robustness of the training set. In this experiment the Chest CT-Scan images Dataset is used which is publicly available in KAGGLE. Which is being further enriched with synthetic images created by DCGAN. While being trained on this augmented dataset the proposed 3D-FusionNet model achieved superior performance in cancer detection. Which shows higher accuracy, sensitivity and specificity than other conventional approaches. The integration of DCGAN with 3D-TDUnet++ together with Non-Local Feature Aggregation (NLFa) made the system promising for clinical environments where limited data often restricts the application of deep learning models. Quantitative evaluation reveals that the proposed 3D-FusionNet achieves a Dice coefficient of 88.94%, F1-score of 88.94% and an accuracy of 93.37%. Outperforming the benchmark models such as DenseNet, ResNet and MDDNet-ASPP. This hybrid design leverages the strengths of generative augmentation and non-local attention to improve both segmentation precision and clinical robustness. Thus the proposed 3D-FusionNet model demonstrates how deep generative modeling and volumetric segmentation can be integrated into a cohesive machine vision system. Which is capable of scalable and efficient deployment in real-world diagnostic pipelines.

Indexed as

Imaging, Three-DimensionalLung NeoplasmsRadiographic Image Interpretation, Computer-AssistedTomography, X-Ray ComputedAlgorithmsDeep LearningHumansNeural Networks, Computer3D-TDUnet++computer-aided diagnosis (CAD)Cross-domain image synthesisDeep Convolutional Generative Adversarial Networks (DCGAN)Non-Local Feature Aggregation (NLFa)Synthetic CT images

Identifiers

PMID41339453
PMCPMC12700945

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.