Effects of transient forebrain ischemia on cognitive performance and cell death in the Cornet d'Ammon 1 (CA1) region of the hippocampus in juvenile (2-month-old) and adult (6-month-old) Mongolian gerbils (Meriones unguiculatus).

Tomohiro Kondo, Yusuke Kataoka, Takayuki Nakajima, Toshiya Okada

Abstract read

In one paragraph

Article in The Journal of veterinary medical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

4 authors.

Tomohiro KondoDepartment of Laboratory Animal Science, Graduate School of Life and Environmental Biosciences, Osaka Prefecture University, Osaka, Japan.

Yusuke KataokaDepartment of Laboratory Animal Science, Graduate School of Life and Environmental Biosciences, Osaka Prefecture University, Osaka, Japan.

Takayuki NakajimaDepartment of Veterinary Anatomy, Graduate School of Life and Environmental Biosciences, Osaka Prefecture University, Osaka, Japan.

Toshiya OkadaDepartment of Laboratory Animal Science, Graduate School of Life and Environmental Biosciences, Osaka Prefecture University, Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Working memory tests were performed on days 8-18 after 5-min cerebral ischemia in juvenile (2-month-old) and adult (6-month-old) gerbils, followed by observation of cell death in the hippocampus on postoperative day 19. Both 2- and 6-month-old ischemic gerbils made significantly more working memory errors than age-matched sham-operated ones. After repeated trials, the number of working memory errors in 2-month-old ischemic gerbils reached the level of sham-operated ones earlier than in 6-month-old gerbils. However, no significant differences were seen in the number of hippocampal cell deaths between 2- and 6-month-old ischemic gerbils. This study revealed that juvenile gerbils recovered from cognitive impairment more quickly than adults, although no difference in hippocampal damage was evident after transient forebrain ischemia.

Indexed as

Brain IschemiaCA1 Region, HippocampalCognitionHippocampusIschemic Attack, TransientProsencephalonAnimalsCell DeathGerbillinaeMaleMemory, Short-Termbehavioral analysisdelayed neuronal cell deathforebrain ischemiaradial maze

Identifiers

PMID41339017

DOI10.1292/jvms.25-0306

PMCPMC12887114

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Textmetadata

LicenceCC BY-NC-ND

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.