ArticleBMJ global health2025
Molecular investigation of
Article in BMJ global health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
19 authors.
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Abstract
backgroundMalaria remains a serious public health threat, especially in Africa. The challenge in detecting low-density
methodsIn 2022, during the COVID-19 pandemic, we conducted a nationally representative, age-stratified cross-sectional epidemiological survey in Sierra Leone during the rainy season to investigate the prevalence of
resultsAmong all 2112 samples, the
conclusionsThis study highlights the importance of molecular diagnosis in malaria-endemic areas for surveillance, diagnosis and treatment. The high prevalence of malaria infection among individuals aged ≥20 years, together with the high prevalence of asymptomatic, low-density infections, indicates a sustained potential transmission reservoir. Additionally, urban and rural malaria prevalence showed no statistically significant difference, a finding that underscores the need for greater attention to urban malaria.
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