Evidence map›Paper›PMID 41338712›Full record

Trial reportJournal of the American College of Radiology : JACR2025

Radiation Dose Associated With CT in the Watch the Spot Trial: A Pragmatic Trial of Less Versus More Intensive Strategies for Active Follow-Up of Patients With Small Pulmonary Nodules.

Rebecca Smith-Bindman, Diana L Miglioretti, Yueju Li, Lihong Qi, Evan de Bie, Beth Creekmur, Debra P Ritzwoller, Kim L Sandler, Debra S Dyer, Karen Kelly and 1 more

Abstract readMulticenter StudyPragmatic Clinical TrialRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Journal of the American College of Radiology : JACR, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Rebecca Smith-BindmanDepartment of Epidemiology and Biostatistics, Department of Obstetrics, Gynecology and Reproductive Sciences, and the Philip R. Lee Institute for Health Policy Studies, University of California, San Francisco, San Francisco, California. Electronic address: rebecca.smith-bindman@ucsf.edu.
Diana L MigliorettiDivision Chief of Biostatistics, Department of Public Health Sciences, University of California, Davis, Davis, California.
Yueju LiDepartment of Public Health Sciences, University of California, Davis, Davis, California.
Lihong QiDepartment of Public Health Sciences, University of California, Davis, Davis, California.
Evan de BieDepartment of Public Health Sciences, University of California, Davis, Davis, California.
Beth CreekmurDepartment of Research & Evaluation, Kaiser Permanente Southern California, Pasadena, California.
Debra P RitzwollerInstitute of Health Research, Kaiser Permanente Colorado, Aurora, Colorado.
Kim L SandlerDepartment of Radiology, Vanderbilt University, Nashville, Tennessee.
Debra S DyerPast Chair, Department of Radiology, National Jewish Health, Denver, Colorado.
Karen KellyCEO, International Association for the Study of Lung Cancer, Denver, Colorado.
Michael K GouldDepartment of Research & Evaluation, Kaiser Permanente Southern California, Pasadena, California; Faculty Director of Research, Department of Health Systems Science, Kaiser Permanente Bernard J. Tyson School of Medicine, Pasadena, California.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWatch the Spot is a cluster-randomized pragmatic clinical trial comparing less versus more intensive surveillance strategies for small pulmonary nodules. This article describes radiation doses from screening and follow-up imaging.

methodsIn all, 34,686 patients with small nodules were enrolled across 24 US sites (March 2017 to July 2019). Dose estimates were available from 21 sites and reported as size-adjusted CT dose index-volume (CTDI

resultsRadiation doses varied substantially across sites. For screening, mean size-adjusted CTDI

conclusionTwo-year cumulative radiation dose was similar for patients in the less and more intensive surveillance arms; however, patient size-adjusted doses both for screening and follow-up CTs varied widely within and across sites and frequently exceeded recommended thresholds.

Indexed as

Lung NeoplasmsMultiple Pulmonary NodulesRadiation DosageSolitary Pulmonary NoduleTomography, X-Ray ComputedAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedUnited StatesCT radiation doselung cancer screeninglung nodule surveillancepulmonary nodulerandomized trial

Identifiers

PMID41338712

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.