ArticleThe American journal of clinical nutrition2025
Male partner pesticide residue exposure from fruit and vegetable intake in relation to outcomes of infertility treatment: a prospective cohort study.
Article in The American journal of clinical nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
backgroundConsuming fruits and vegetables (FVs) with high pesticide residues has been related to lower sperm counts. Whether this translates into lower fertility is unclear.
objectivesTo test the hypothesis that male preconception intake of FV with high pesticide residue levels is associated with lower success rates in infertility treatment outcomes.
methodsIn a prospective cohort, 244 males (median age: 36.6 y) and their female partners (median age: 35 y) underwent 437 assisted reproductive technology (ART) cycles for infertility treatment in 2007-2021 (Massachusetts General Hospital). The United States Department of Agriculture food pesticide residue surveillance data were used to assess pesticide residue exposure from FV intake. Associations of FVs with high and low pesticide residue with ART outcomes [fertilization rate, low fertilization (<50%), implantation, clinical pregnancy, pregnancy loss, and live birth] were evaluated using generalized linear mixed models.
resultsIntake of FVs with high pesticide residue was inversely associated with fertilization rate, whereas intake of FVs with low pesticide residue was positively associated with fertilization rate. The adjusted fertilization rates for couples with a male partner in the lowest and highest quartiles of intake were 0.78 [95% confidence interval (CI): 0.73, 0.83] and 0.69 (95% CI: 0.62, 0.75) for FVs with high pesticide residue (P
conclusionsIntake of FVs with high pesticide residue in males is associated with adverse infertility treatment outcomes with ART, particularly in conventional insemination cycles. Implications for natural fertility are unclear.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.