Evidence map›Paper›PMID 41338648›Full record

ArticleBMJ open2025

How do musculoskeletal disorders impact on quality of life in Tanzania? Results from a community-based survey.

Eleanor Grieve, Manuela Deidda, Stefanie J Krauth, Sanjura Mandela Biswaro, Jo E B Halliday, Ping-Hsuan Hsieh, Clive Kelly, Kajiru Kilonzo, Kiula P Kiula, Rose Kolimba and 7 more

Abstract read
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Eleanor GrieveSchool of Health and Wellbeing, Health Economics and Health Technology Assessment, University of Glasgow College of Medical Veterinary and Life Sciences, Glasgow, UK Eleanor.Grieve@glasgow.ac.uk.ORCID http://orcid.org/0000-0002-4115-2882
Manuela DeiddaSchool of Health and Wellbeing, Health Economics and Health Technology Assessment, University of Glasgow College of Medical Veterinary and Life Sciences, Glasgow, UK.ORCID http://orcid.org/0000-0002-0921-6970
Stefanie J KrauthSchool of Health and Wellbeing, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
Sanjura Mandela BiswaroKilimanjaro Christian Medical Centre, Moshi, Tanzania, United Republic of.
Jo E B HallidaySchool of Biodiversity, One Health and Veterinary Medicine, University of Glasgow College of Medical Veterinary and Life Sciences, Glasgow, UK.ORCID http://orcid.org/0000-0002-1329-9035
Ping-Hsuan HsiehNational Defense Medical University, Taipei City, Taiwan.ORCID http://orcid.org/0000-0002-0430-260X
Clive KellyJames Cook University Hospital, Middlesbrough, UK.
Kajiru KilonzoKilimanjaro Christian Medical Centre, Moshi, Tanzania, United Republic of.
Kiula P KiulaKilimanjaro Clinical Research Institute, Moshi Urban, Kilimanjaro Region, Tanzania, United Republic of.ORCID http://orcid.org/0000-0002-6860-5474
Rose KolimbaKilimanjaro Clinical Research Institute, Moshi Urban, Kilimanjaro Region, Tanzania, United Republic of.
Elizabeth F MsokaKCMC University, Moshi Urban, Kilimanjaro Region, Tanzania, United Republic of.ORCID http://orcid.org/0000-0002-2352-3520
Stefan SiebertSchool of Infection and Immunity, University of Glasgow College of Medical Veterinary and Life Sciences, Glasgow, UK.ORCID http://orcid.org/0000-0002-1802-7311
Richard WalkerPopulation Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.
Nateiya Mmeta YongoloKilimanjaro Clinical Research Institute, Moshi Urban, Kilimanjaro Region, Tanzania, United Republic of.ORCID http://orcid.org/0000-0002-9659-7926
Blandina MmbagaKilimanjaro Christian Medical Centre, Moshi, Tanzania, United Republic of.
Emma McIntoshSchool of Health and Wellbeing, Health Economics and Health Technology Assessment, University of Glasgow College of Medical Veterinary and Life Sciences, Glasgow, UK.
NIHR Global Health Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThere are little available data on the prevalence, economic and quality of life impacts of musculoskeletal disorders in sub-Saharan Africa. This lack of evidence is wholly disproportionate to the significant disability burden of musculoskeletal disorders as reported in high-income countries. Our research aimed to undertake an adequately powered study to identify, measure and value the health impact of musculoskeletal conditions in the Kilimanjaro region, Tanzania.

designA community-based cross-sectional survey was undertaken between January 2021 and September 2021. A two-stage cluster sampling with replacement and probability proportional to size was used to select a representative sample of the population.

settingThe survey was conducted in 15 villages in the Hai District, Kilimanjaro region, Tanzania.

participantsEconomic and health-related quality of life (HRQOL) questionnaires were administered to a sample of residents (aged over 5 years old) in selected households (N=1050). There were a total of 594 respondents, of whom 153 had a confirmed musculoskeletal disorder and 441 matched controls. Almost three-quarters of those identified as having a musculoskeletal disorder were female and had an average age of 66 years. PRIMARY AND SECONDARY OUTCOME MEASURES: Questions on healthcare resource use, expenditure and quality of life were administered to all participants, with additional more detailed economic and quality of life questions administered to those who screened positive, indicating probable arthritis.

resultsThere is a statistically significant reduction in HRQOL, on average 25% from a utility score of 0.862 (0.837, 0.886) to 0.636 (0.580, 0.692) for those identified as having a musculoskeletal disorder compared with those without. The attributes 'pain' and 'discomfort' were the major contributors to this reduction in HRQOL.

conclusionsThis research has revealed a significant impact of musculoskeletal conditions on HRQOL in the Hai district in Tanzania. The evidence will be used to guide clinical health practices, interventions design, service provisions and health promotion and awareness activities at institutional, regional and national levels.

Indexed as

Musculoskeletal DiseasesQuality of LifeAdolescentAdultAgedCost of IllnessCross-Sectional StudiesFemaleHumansMaleMiddle AgedSurveys and QuestionnairesTanzaniaYoung AdultCross-Sectional StudiesHEALTH ECONOMICSMusculoskeletal disordersQuality of Life

Identifiers

PMID41338648
PMCPMC12706106

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.