ArticleJournal of gastroenterology and hepatology2026
The Saline-Immersion/Irrigation TEchnique for Endoscopic Submucosal Dissection of Colorectal Lesions: Outcomes From a Large Western Cohort.
Article in Journal of gastroenterology and hepatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Saline-immersion technique for endoscopic submucosal dissection with traction for an ileocecal adenoma involving the ileal outlet.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2026Article
- The Saline-Immersion/Irrigation TEchnique for Endoscopic Submucosal Dissection of Colorectal Lesions: Outcomes From a Large Western Cohort.Journal of gastroenterology and hepatology · 2026Article
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6 authors.
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Abstract
BACKGROUND AND STUDY
aimsEndoscopic submucosal dissection (ESD) is increasingly used for the resection of complex lesions of the gastrointestinal tract. However, its adoption in the management of colonic lesions in Western practice remains challenging, mainly due to the anatomical complexities of the colon. The saline-immersion/irrigation technique (SITE), combined with the pocket-creation method (PCM) may help to overcome these challenges. This study evaluates outcomes of SITE-PCM ESD in a Western tertiary center.
methodsWe analyzed consecutive colorectal ESD procedures performed at our center between 2017 and 2024. SITE-PCM was used in all cases. Lesion characteristics, procedural outcomes, histopathological findings, adverse events, and follow-up data were analyzed.
resultsA total of 181 lesions in 177 patients were resected en bloc using SITE-PCM ESD. Sixty lesions (33.1%) were located in the proximal colon, while 79 (43.6%) were rectal lesions. R0 and curative resection rates were 92.3% and 90.6%, respectively. The median procedure time was 120 min. Adverse events occurred in 4.4% of cases, with only three patients necessitating hospitalization and nonsurgical intervention due to delayed bleeding, and one patient requiring surgical management after a delayed perforation. Notably, 93.4% of the procedures were performed under conscious sedation.
conclusionsIn our experience SITE-PCM-ESD appears to be a safe and effective minimally invasive approach for complex colorectal lesions. It achieves high R0 and curative resection rates with low adverse events and is feasible under conscious sedation. These findings support broader adoption of SITE-PCM in Western practice and justify prospective multicenter validation.
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