Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
J Andrew D Nelson *Department of Biochemistry and Biophysics, The University of Pennsylvania, Philadelphia, PA 19104.ORCID 0000-0002-1413-3766
Samuel E Garfinkle *Department of Biochemistry and Biophysics, The University of Pennsylvania, Philadelphia, PA 19104.ORCID 0000-0001-7729-9299
Zi Jie LinVaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA 19104.
Joyce ParkVaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA 19104.
Amber J KimVaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA 19104.
Kelly BayrunsVaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA 19104.
Madison E McCannaVaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA 19104.
Kylie M KonrathBiomedical Graduate Studies, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104.
Colby J AgostinoDepartment of Biochemistry and Biophysics, The University of Pennsylvania, Philadelphia, PA 19104.ORCID 0000-0002-1864-1848
Daniel W KulpDepartment of Biochemistry and Biophysics, The University of Pennsylvania, Philadelphia, PA 19104.
Audrey R Odom JohnBiomedical Graduate Studies, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104.ORCID 0000-0001-8395-8537
Jesper PallesenDepartment of Biochemistry and Biophysics, The University of Pennsylvania, Philadelphia, PA 19104.ORCID 0000-0002-3270-1587
Funding
MEP pathway resistance in Plasmodium falciparumR01AI103280 · NIAID · WASHINGTON UNIVERSITY · PI Audrey Ragan Odom John · 2013 to 2026
$5.5M
Structural biology and molecular biophysics training programT32GM132039 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI Ben E. Black, Elizabeth Rhoades · 2019 to 2026
$3.3M
A New Cryo-Transmission Electron Microscope at Thomas Jefferson UniversityS10OD030457 · OD · THOMAS JEFFERSON UNIVERSITY · PI CINGOLANI, GINO · 2022 to 2022
$2.0M
HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R01AI103280HHS | NIH | National Institute of General Medical Sciences (NIGMS) 2T32GM132039NIAID NIH HHS R01 AI103280NIGMS NIH HHS T32 GM132039NIH HHS S10 OD030457
6 · The paper itself
Abstract
Currently approved vaccines for the prevention of malaria provide only partial protection against disease due to high variability in the quality of induced antibodies. These vaccines present the unstructured central repeat region, as well as the C-terminal domain, of the circumsporozoite protein (
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Machine learning enables de novo multiepitope design of · full record | OpenQuestion