Evidence map›Paper›PMID 41335450›Full record

ArticleBioinformatics (Oxford, England)2025

COCOMAPS 2.0: a web server for identifying, analyzing, and visualizing atomic interactions at the interface of biomolecular complexes.

Mohit Chawla, Utkarsh Kalra, Andrea Petta, Suraj Sharma, Abdul Rajjak Shaikh, Luigi Cavallo, Romina Oliva

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
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  10. Bioinformatics and biology insights · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Frontiers in cellular and infection microbiology · 2026
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mohit ChawlaPhysical Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi Arabia.ORCID 0000-0002-3332-3055
Utkarsh KalraPhysical Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi Arabia.
Andrea PettaTagetik Software S.R.L, Lucca 55100, Italy.
Suraj SharmaDepartment of Research and Innovation, STEMskills Research and Education Lab Private Limited, Faridabad 121002, Haryana, India.
Abdul Rajjak ShaikhDepartment of Sciences and Technologies, University "Parthenope" of Naples, Naples 80143, Italy.
Luigi CavalloPhysical Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi Arabia.ORCID 0000-0002-1398-338X
Romina OlivaDepartment of Sciences and Technologies, University "Parthenope" of Naples, Naples 80143, Italy.ORCID 0000-0002-6156-6249

Funding

KAUST URF/1/4384-01-01KAUST URF/1/4701-01-01Ministero dell'Università e della Ricerca, MURNextGeneration EU PRIN 2022HREZJT
6 · The paper itself

Abstract

summaryHerein, we present COCOMAPS 2.0, for the analysis, visualization, and comparison of the interface in protein-protein and protein-nucleic acid complexes. COCOMAPS 2.0 complements the residue-level and buried surface area analyses of the original COCOMAPS tool with a comprehensive and accurate atomic-level characterization of the interface, enabling detailed interpretation of molecular recognition. Furthermore, it provides a greatly enhanced flexibility, interactivity, and efficiency in graphical visualizations. AVAILABILITY AND IMPLEMENTATION: COCOMAPS 2.0 is accessible as a public web tool at https://aocdweb.com/BioTools/cocomaps2 and as a standalone code at https://doi.org/10.5281/zenodo.17390665.

Indexed as

Nucleic AcidsProteinsSoftwareInternetModels, MolecularProtein BindingNucleic AcidsProteins

Identifiers

PMID41335450
PMCPMC12684709

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.