ArticlePhotochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology2026
Biopolymeric stabilization of photonic nanoaggregates using amaranth starch: toward applications in bioimaging and photodynamic therapy.
Article in Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
In this work, the development of π-conjugated chromophore nanoparticles using starch as a biopolymer stabilizer is reported. Starch was extracted from Amaranthus hypochondriacus seeds via an environmentally friendly aqueous method. The extracted starch served as a biocompatible stabilizing matrix for the preparation of nanosystems incorporating bisquinoline derivatives (BQ1 and BQ2) and a diketopyrrolopyrrole derivative (DPP-BisTPA) through a controlled reprecipitation process in an aqueous medium. The starch-stabilized nanoaggregates exhibited average hydrodynamic diameters of less than 100 nm, as determined by DLS, and negative zeta potential values, indicating colloidal stability. UV-Vis and photoluminescence analyses indicate that starch encapsulation does not alter the NLO or AIE properties of the model fluorophores (BQ1 and BQ2). Similarly, the model photosensitizer (DPP-BisTPA) maintains its singlet oxygen generation efficiency. Overall, these starch-derived nanosystems represent a biodegradable and sustainable platform for the development of nanophotosensitisers and fluorescent probes with potential applications in bioimaging and photodynamic therapy.
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