Evidence map›Paper›PMID 41335263›Full record

ReviewPlant foods for human nutrition (Dordrecht, Netherlands)2025

Synergy Between Lycopene and Food Components: a Review on the Mechanisms and Health Effects.

Eduardo Macedo de Melo, Gabriela Polmann, Jane Mara Block

Abstract readReview
PubMed Publisher
In one paragraph

Review in Plant foods for human nutrition (Dordrecht, Netherlands), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Eduardo Macedo de MeloGraduate Program in Food Science - Department of Food Science and Technology, Federal University of Santa Catarina, Florianópolis, Brazil.ORCID http://orcid.org/0000-0003-3258-2730
Gabriela PolmannGraduate Program in Food Engineering - Department of Chemical and Food Engineering, Federal University of Santa Catarina, Florianópolis, Brazil.ORCID http://orcid.org/0000-0002-8062-7385
Jane Mara BlockGraduate Program in Food Science - Department of Food Science and Technology, Federal University of Santa Catarina, Florianópolis, Brazil. janeblock@gmail.com.ORCID http://orcid.org/0000-0003-3781-3366

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 313163/2021-9Coordenação de Aperfeiçoamento de Pessoal de Nível Superior PROEX 1513/2023Fundação de Amparo à Pesquisa e Inovação do Estado de Santa Catarina 20/2024Fundação de Amparo à Pesquisa e Inovação do Estado de Santa Catarina 735/2024
6 · The paper itself

Abstract

Lycopene is an important carotenoid in human diet with strong antioxidant power and other bioactive functions. As it is sourced from fruits and vegetables, this phytochemical is bound to interact with food components as it is absorbed and metabolized in the organism. Understanding the nature and implications of such interactions is crucial for the prevention of chronic diseases, accurate dietary recommendations and the development of new functional foods, supplements and nutraceuticals. In this review, we explore and discuss current literature on the synergistic effects derived from the combination of lycopene with food phytochemicals, micronutrients and macronutrients. Here, we have focused on peer-reviewed data of in vitro and in vivo studies that brings insights regarding the biochemical mechanisms and health implications of the synergy resulting from the positive interaction between lycopene and food components. We also added some food for thought regarding future research on the matter and a disclosure about the limitations of the review.

Indexed as

AntioxidantsCarotenoidsLycopenePhytochemicalsAnimalsDietDietary SupplementsFruitFunctional FoodHumansMicronutrientsVegetablesAntioxidantsCarotenoidsLycopeneMicronutrientsPhytochemicalsAntioxidant activityCarotenoidsDietary nutrientsFood nutritionNutrient interactions

Identifiers

PMID41335263

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.