Evidence map›Paper›PMID 41335096›Full record

ArticleNucleic acids research2026

ResMicroDb: a comprehensive database and analysis platform for the human respiratory microbiome.

Xiaotong Ji, Qiheng Qian, Hao Zhang, Qingyun Cai, Kaiwen Zhang, Jingfa Xiao, Xiaoqing Jiang, Mingkun Li

Abstract read
In one paragraph

Article in Nucleic acids research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiaotong JiChina National Center for Bioinformation, Beijing 100101, China.
Qiheng QianBeijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China.ORCID 0000-0002-1930-7171
Hao ZhangChina National Center for Bioinformation, Beijing 100101, China.
Qingyun CaiChina National Center for Bioinformation, Beijing 100101, China.
Kaiwen ZhangChina National Center for Bioinformation, Beijing 100101, China.
Jingfa XiaoBeijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China.ORCID 0000-0002-2835-4340
Xiaoqing JiangChina National Center for Bioinformation, Beijing 100101, China.
Mingkun LiChina National Center for Bioinformation, Beijing 100101, China.ORCID 0000-0003-1041-1172

Funding

Chinese Academy of Sciences XDA0460202Chinese Academy of Sciences XDA0460404National Key R&D Program of China 2022YFA1304300National Key R&D Program of China 2024YFC2607900National Natural Science Foundation of China 32300078
6 · The paper itself

Abstract

The respiratory microbiome plays an important role in maintaining human health. Despite the rapid growth of literature and publicly accessible data on the respiratory microbiome, a large-scale, well-curated database is still lacking. Here, we introduced ResMicroDb, a comprehensive database and analysis platform for the human respiratory microbiome. ResMicroDb contains 106 464 samples from 514 projects, spanning 10 sample sites, 72 sample types, and 146 phenotypes. Notably, it includes ~7-fold more respiratory samples than existing multi-body-site resources. To improve the reusability and accessibility of data, a standardized bioinformatics pipeline was employed to generate taxonomic profiles, and 32 metadata fields were manually curated. ResMicroDb also provides 11 908 microbe-disease associations, identified from 132 case-control studies, to deepen the understanding of microbiome-disease relationships. Additionally, ResMicroDb offers three tools for in-depth analysis: "Microbiome Composition" for visualizing taxonomic profiles of user-selected samples; "Sample Similarity Search" for inferring the characteristics of new samples by comparing them to the database based on similarity; and "Cross-study Analysis" for identifying common and specific microbial characteristics across cohorts, phenotypes and sample sites. ResMicroDb serves as a versatile and valuable resource for advancing a broad spectrum of respiratory microbiome research and clinical relevance. ResMicroDb is freely accessed at https://resmicrodb.cncb.ac.cn.

Indexed as

Databases, FactualMicrobiotaRespiratory SystemCase-Control StudiesComputational BiologyHumansSoftware

Identifiers

PMID41335096
PMCPMC12807670

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.