Evidence map›Paper›PMID 41335051›Full record

ArticleJACC. Case reports2026

Managing Unrepaired Tetralogy of Fallot in Pregnancy: A Rare Case Defying Standard Cardiac Guidelines.

Talha Farooq, Hannah S Asghar, Babar Hasan, Abeer Riaz, Veena Kumari, Reema Qayoom

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Talha FarooqJinnah Sindh Medical University, Karachi, Pakistan. Electronic address: farooqtalha41@gmail.com.
Hannah S AsgharNational Institute of Cardiovascular Diseases, Karachi, Pakistan.
Babar HasanSindh Institute of Urology and Transplantation, Karachi, Pakistan.
Abeer RiazJinnah Sindh Medical University, Karachi, Pakistan.
Veena KumariNational Institute of Cardiovascular Diseases, Karachi, Pakistan.
Reema QayoomNational Institute of Cardiovascular Diseases, Karachi, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTetralogy of Fallot (TOF) is the commonest cyanotic congenital cardiac defect. Uncorrected TOF in adults, especially during pregnancy, is uncommon and presents significant hazards to both mother and fetus. SUMMARY: We present a case of a 28-year-old lady with uncorrected cyanotic TOF, gravida 4, para 1 + 3 at 22 weeks of gestation, who presented to our multidisciplinary cardio-obstetric team. She presented with cyanosis, exertional dyspnea, and oxygen saturation in the range of 70% to 80%. Echocardiography revealed the classic features of TOF, such as a large ventricular septal defect and severe pulmonary stenosis. An emergency preterm birth was performed at 28 weeks due to maternal instability. The baby, admitted to the neonatal intensive care unit, was released after 14 days. DISCUSSION: Uncorrected TOF seldom allows for survival to reproductive age. Research indicates worse maternal-fetal outcomes in such cases. This instance underscores the significance of prompt diagnosis and diligent management by a multidisciplinary cardio-obstetric team for a better prognosis.

conclusionsUncorrected TOF during pregnancy is uncommon but can be effectively managed with prompt, multidisciplinary cardio-obstetric collaborative intervention.

Indexed as

congenital heart defecthigh-risk pregnancymultidisciplinary approachtetralogy of Fallot

Identifiers

PMID41335051
PMCPMC12926320

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.