Evidence map›Paper›PMID 41335004›Full record

ReviewAnaesthesia2026

Developments in nitrous oxide capture technologies: bridging current research to clinical applications.

Simon Molisso, Ashleigh M Chester, Elmira Baghdaran, Jennifer Waspe, Peyman Z Moghadam

Abstract readReview
In one paragraph

Review in Anaesthesia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Simon MolissoDepartment of Chemical Engineering, University College London, London, UK.ORCID 0000-0002-4210-0275
Ashleigh M ChesterDepartment of Chemical Engineering, University College London, London, UK.ORCID 0000-0003-4605-6651
Elmira BaghdaranNevill Hall Hospital, Aneurin Bevan University Health Board, Abergavenny, UK.
Jennifer WaspeSheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.ORCID 0000-0001-8538-7299
Peyman Z MoghadamDepartment of Chemical Engineering, University College London, London, UK.ORCID 0000-0002-1592-0139

Funding

Association of Anaesthetists NIAA23R107The Maurice Freeman Barema
6 · The paper itself

Abstract

introductionMany inhaled anaesthetic agents are greenhouse gases. Capture technologies have been developed to prevent environmental emissions of volatile agents, but no such devices exist for nitrous oxide. Further to this, the unique societal position of the use of nitrous oxide for patients in labour means it cannot readily be substituted for alternatives. Currently, there are no mandated scavenging systems for nitrous oxide in maternity wards, resulting in not only loss to the environment, but also occupational exposure among labour ward staff, often at levels well above regulatory limits. Without a suitable analgesic alternative, and with contemporary catalytic destruction (cracking) devices for nitrous oxide relatively underutilised, more work must be done to develop capture technologies. While nitrous oxide capture for anaesthetic purposes is severely under-researched, a wide range of literature exists for other applications, including directly from the atmosphere and from waste effluent during chemical processing.

methodsA literature search was used to identify original research articles describing adsorbents for nitrous oxide uptake. The search was limited to published articles over the last 5 years and relevance was screened by abstract review.

resultsDifferent classes of adsorbents that could be used for nitrous oxide capture include activated charcoals, zeolites and metal-organic frameworks. We highlight their important properties and describe their key drawbacks. Recent literature was also examined and strategies in nitrous oxide capture across different industries drawn together to address the unique scenario of maternity analgesia. DISCUSSION: Metal-organic frameworks are identified as a promising class of porous adsorbents that could be applied to a wide range of anaesthetic settings. With over 100,000 structures identified, they have a remarkable tuneability which should be further exploited in clinical settings to not only further progress towards 'net zero' targets but also to improve safety outcomes.

Indexed as

Anesthetics, InhalationNitrous OxideHumansOccupational ExposureAnesthetics, InhalationNitrous Oxidematernity wardsmetal–organic frameworksnitrous oxidevolatile anaesthetic gasesvolatile capture technology

Identifiers

PMID41335004
PMCPMC12893838

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.