Evidence map›Paper›PMID 41334980›Full record

ArticleJournal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.]2026

Fatigue Performance and Failure Loads of Composition-Gradient Multilayer Zirconia: Partial-Coverage Restorations Versus Single Crowns at Different Thicknesses.

F A Spitznagel, A Marksteiner, L S Prott, Y Zhang, M B Blatz, L M M Alves, T M B Campos, P C Gierthmuehlen

Abstract read
In one paragraph

Article in Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.], 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

F A SpitznagelDepartment of Prosthodontics, Medical Faculty and University Hospital Düsseldorf, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.ORCID https://orcid.org/0000-0001-5535-2108
A MarksteinerDepartment of Prosthodontics, Medical Faculty and University Hospital Düsseldorf, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
L S ProttDepartment of Prosthodontics, Medical Faculty and University Hospital Düsseldorf, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.ORCID https://orcid.org/0000-0003-0792-0830
Y ZhangDepartment of Preventive and Restorative Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-6738-3769
M B BlatzDepartment of Preventive and Restorative Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID https://orcid.org/0000-0001-6341-7047
L M M AlvesDepartment of Prosthodontics and Periodontology, Bauru School of Dentistry, University of Sao Paulo, Bauru, Brazil.ORCID https://orcid.org/0000-0003-4561-0980
T M B CamposDepartment of Prosthodontics and Periodontology, Bauru School of Dentistry, University of Sao Paulo, Bauru, Brazil.
P C GierthmuehlenDepartment of Prosthodontics, Medical Faculty and University Hospital Düsseldorf, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.ORCID https://orcid.org/0000-0002-4837-2546

Funding

International College of Prosthodontist
6 · The paper itself

Abstract

objectiveThis study investigated the influence of restoration type (partial-coverage versus crown) and ceramic-layer thickness on the fatigue behavior and failure load of monolithic composition-gradient multilayer zirconia (4Y-PSZ/5Y-PSZ) molar restorations. MATERIAL AND

methodsSeventy-two CAD/CAM-fabricated monolithic zirconia restorations (IPS e.max ZirCAD-Prime-Esthetic, Ivoclar-Vivadent) were assigned to six groups (n = 12), based on restoration type-partial-coverage restoration (PCR) or crown (C)-and ceramic thickness (occlusal/buccal: 0.5/0.4, 1.0/0.6, or 1.5/0.8 mm). All restorations were adhesively bonded to standardized dentin-analogue dies. Specimens underwent thermomechanical fatigue (1.2 million cycles, 49 N, 1.6 Hz, 5°C-55°C), followed by single load to failure testing. Data were analyzed using ANOVA, Tukey's post hoc test, and independent t-tests (α = 0.05).

resultsAll specimens survived fatigue. Evident cracks were observed post-fatigue; one each in PCR-0.5 and C-0.5 groups, resulting in an overall success rate of 97.22%. Mean failure loads (N) were: PCR-0.5: 2047, PCR-1.0: 2018, PCR-1.5: 2777, C-0.5: 695, C-1.0: 1957, C-1.5: 3503. Ultrathin (0.5 mm) PCRs demonstrated significantly higher failure loads than ultrathin crowns (p < 0.001), whereas crowns at 1.5 mm thickness outperformed PCRs (p = 0.005). No significant difference was observed at 1.0 mm thickness (p = 0.634).

conclusionAt ultrathin thicknesses (0.5 mm), partial-coverage designs showed superior failure loads over crowns. Both restoration types are mechanically viable at 1.0 mm and 1.5 mm thicknesses. CLINICAL SIGNIFICANCE: Composition-gradient multilayer-zirconia demonstrates high fatigue resistance and is well-suited for minimally invasive, non-retentive PCR molar restorations. However, a minimum thickness of 1.0 mm should be maintained for single crowns.

Indexed as

CrownsDental MaterialsDental Restoration FailureZirconiumComputer-Aided DesignDental Prosthesis DesignDental Stress AnalysisHumansMaterials TestingDental MaterialsZirconiumzirconium oxideceramicsceramic thicknesscomputer‐aided designfatiguepartial‐coverage restoration

Identifiers

PMID41334980
PMCPMC13062717

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.