Evidence map›Paper›PMID 41334910›Full record

ArticleJournal of virology2025

Avian coronavirus IBV-induced activation of the NLRP3-Caspase-1-IL-1β axis in renal collecting ducts contributes to nephropathogenesis.

Min Huang, Chengyin Liukang, Rong Liang, Yingfei Li, Ruihua Yang, Mingwei Zhang, Ye Zhao, Jing Zhao, Guozhong Zhang

Abstract read
In one paragraph

Article in Journal of virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Min HuangState Key Laboratory of Veterinary Public Health and Safety, College of Veterinary Medicine, China Agricultural University, Beijing, People's Republic of China.
Chengyin LiukangState Key Laboratory of Veterinary Public Health and Safety, College of Veterinary Medicine, China Agricultural University, Beijing, People's Republic of China.
Rong LiangState Key Laboratory of Veterinary Public Health and Safety, College of Veterinary Medicine, China Agricultural University, Beijing, People's Republic of China.
Yingfei LiState Key Laboratory of Veterinary Public Health and Safety, College of Veterinary Medicine, China Agricultural University, Beijing, People's Republic of China.
Ruihua YangState Key Laboratory of Veterinary Public Health and Safety, College of Veterinary Medicine, China Agricultural University, Beijing, People's Republic of China.
Mingwei ZhangState Key Laboratory of Veterinary Public Health and Safety, College of Veterinary Medicine, China Agricultural University, Beijing, People's Republic of China.
Ye ZhaoState Key Laboratory of Veterinary Public Health and Safety, College of Veterinary Medicine, China Agricultural University, Beijing, People's Republic of China.
Jing ZhaoState Key Laboratory of Veterinary Public Health and Safety, College of Veterinary Medicine, China Agricultural University, Beijing, People's Republic of China.ORCID 0009-0006-1985-4809
Guozhong ZhangState Key Laboratory of Veterinary Public Health and Safety, College of Veterinary Medicine, China Agricultural University, Beijing, People's Republic of China.ORCID 0000-0002-8200-312X

Funding

2115 Talent Development Program of China Agricultural UniversityNational Natural Science Foundation of China 32272986
6 · The paper itself

Abstract

Avian coronavirus infectious bronchitis virus (IBV) induces severe renal inflammation and urate deposition in chickens, but the underlying mechanisms remain incompletely understood. Here, we used both IMPORTANCE:

Indexed as

Caspase 1Coronavirus InfectionsGammacoronavirusInfectious bronchitis virusInterleukin-1betaKidney Tubules, CollectingNephritisNLR Family, Pyrin Domain-Containing 3 ProteinAnimalsAquaporin 2Chick EmbryoChickensDisease Models, AnimalInflammasomesInflammationPrimary Cell CultureAquaporin 2Caspase 1InflammasomesInterleukin-1betaNLR Family, Pyrin Domain-Containing 3 Proteincollecting duct epithelial cellsinfectious bronchitis virusinflammation-mediated pathologyNLRP3 inflammasomerenal inflammation

Identifiers

PMID41334910
PMCPMC12724324

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.