In one paragraphArticle in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
36 authors.
Minwoo LeeDepartment of Neurology Hallym University Sacred Heart Hospital Anyang-si Republic of Korea.ORCID 0000-0001-8474-5744 Mi-Sun OhDepartment of Neurology Hallym University Sacred Heart Hospital Anyang-si Republic of Korea.ORCID 0000-0002-6741-0464 Kyung-Ho YuDepartment of Neurology Hallym University Sacred Heart Hospital Anyang-si Republic of Korea.ORCID 0000-0002-8997-5626 Byung-Chul LeeDepartment of Neurology Hallym University Sacred Heart Hospital Anyang-si Republic of Korea.ORCID 0000-0002-3885-981X Beom Joon KimDepartment of Neurology and Cerebrovascular Center Seoul National University Bundang Hospital Seongnam-si Republic of Korea.ORCID 0000-0002-2719-3012 Jun Yup KimDepartment of Neurology and Cerebrovascular Center Seoul National University Bundang Hospital Seongnam-si Republic of Korea.ORCID 0000-0003-4764-5714 Jihoon KangDepartment of Neurology and Cerebrovascular Center Seoul National University Bundang Hospital Seongnam-si Republic of Korea.ORCID 0000-0001-5715-6610 Do Yeon KimDepartment of Neurology and Cerebrovascular Center Seoul National University Bundang Hospital Seongnam-si Republic of Korea.ORCID 0000-0003-1123-637X Jong-Moo ParkUijeongbu Eulji Medical Center Eulji University School of Medicine Uijeongbu Republic of Korea.ORCID 0000-0002-4199-3024 Jeong-Yoon LeeDepartment of Neurology Soonchunhyang University Hospital Seoul Seoul Republic of Korea.ORCID 0000-0002-4297-1791 Kyung Bok LeeDepartment of Neurology Soonchunhyang University Hospital Seoul Seoul Republic of Korea.ORCID 0000-0003-2663-7483 Keun-Sik HongDepartment of Neurology Inje University Ilsan Paik Hospital Goyang-si Republic of Korea.ORCID 0000-0002-4684-6111 Hong-Kyun ParkDepartment of Neurology Inje University Ilsan Paik Hospital Goyang-si Republic of Korea.ORCID 0000-0002-8120-2469 Yong-Jin ChoDepartment of Neurology Inje University Ilsan Paik Hospital Goyang-si Republic of Korea.ORCID 0000-0001-6965-0771 Sang-Hwa LeeDepartment of Neurology Chuncheon Sacred Heart Hospital Chuncheon Republic of Korea.
Dong-Ick ShinDepartment of Neurology Chungbuk National University Hospital Cheongju Republic of Korea.ORCID 0000-0001-5770-0268 Kyu Sun YumDepartment of Neurology Chungbuk National University Hospital Cheongju Republic of Korea.ORCID 0000-0001-9815-7652 Juneyoung LeeDepartment of Biostatistics Korea University College of Medicine Seoul Republic of Korea.ORCID 0000-0001-8073-9304 Ji Sung LeeClinical Research Center, Asan Institute for Life Sciences, Asan Medical Center University of Ulsan College of Medicine Seoul Korea.ORCID 0000-0001-8194-3462 Philip B GorelickDavee Department of Neurology Northwestern University Feinberg School of Medicine Chicago IL USA.ORCID 0000-0002-1181-614X Hee-Joon BaeDepartment of Neurology and Cerebrovascular Center Seoul National University Bundang Hospital Seongnam-si Republic of Korea.ORCID 0000-0003-0051-1997 CRCS‐K Investigators *
Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
backgroundThe optimal duration of dual antiplatelet therapy (DAPT) with aspirin plus clopidogrel following acute ischemic stroke due to large-artery atherosclerosis remains uncertain.
methodsWe retrospectively analyzed data from a prospective, multicenter stroke registry (2011-2018) linked to a national health insurance claims database. Patients included had acute ischemic stroke attributable to large-artery atherosclerosis, initiated DAPT within 48 hours of admission and remained free of primary outcome events during the first 30 days. Temporal trends in DAPT usage were evaluated, and landmark analyses assessed the impact of DAPT continuation for up to 6 months after stroke on clinical outcomes. The primary outcome was a composite of recurrent stroke, myocardial infarction, major bleeding, and all-cause death within 1.5 years post-stroke.
resultsA total of 4814 patients (mean age, 68.1±11.8 years; 64.1% men) were analyzed. The median duration of DAPT significantly increased from 36 days in 2011 to 122 days in 2018 (
conclusionsIn patients with acute ischemic stroke due to large-artery atherosclerosis, DAPT duration has lengthened over time and continuation beyond 3 months appears to confer net clinical benefits, without increasing the risk of major bleeding.
Indexed as
AspirinAtherosclerosisClopidogrelDual Anti-Platelet TherapyIntracranial ArteriosclerosisIschemic StrokePlatelet Aggregation InhibitorsAgedAged, 80 and overDrug Therapy, CombinationFemaleHemorrhageHumansMaleMiddle AgedRecurrenceAspirinClopidogrelPlatelet Aggregation Inhibitorsantiplatelet agentsdeathdual antiplatelet therapyischemic strokelarge‐artery atherosclerosisstroke recurrence
Identifiers
PMID41334741
PMCPMC12826892
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