Evidence map›Paper›PMID 41334692›Full record

ArticleAnimal models and experimental medicine2025

A novel inhaled anesthesia technique for concurrent direct laryngoscopy in rats.

Corinne Negvesky, Amin Mirzaaghasi, Eric M Smith, Ashley E Kita

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Animal models and experimental medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Corinne NegveskyDepartment of Head and Neck Surgery, David Geffen School of Medicine University of California, Los Angeles, California, USA.ORCID 0009-0002-5814-6590
Amin MirzaaghasiDepartment of Head and Neck Surgery, David Geffen School of Medicine University of California, Los Angeles, California, USA.ORCID 0000-0001-6015-1247
Eric M SmithDepartment of Head and Neck Surgery, David Geffen School of Medicine University of California, Los Angeles, California, USA.ORCID 0000-0002-1262-3112
Ashley E KitaDepartment of Head and Neck Surgery, David Geffen School of Medicine University of California, Los Angeles, California, USA.ORCID 0000-0002-2759-8271

Funding

Prolonged Local Melatonin Delivery for Recurrent Laryngeal Nerve NeuropraxiaK08DC019957 · NIDCD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Ashley Kita · 2022 to 2026
$1.1M
NIDCD NIH HHS K08 DC019957
6 · The paper itself

Abstract

The current anesthetic standard for laryngoscopy in rats utilizes injectable intraperitoneal anesthesia. Injectable anesthesia is suboptimal for short procedures due to variability in anesthesia duration and anesthetic side effects. Conversely, inhalational gas anesthesia offers precise titration with a rapid onset and offset. However, its use during laryngoscopy has not been documented due to existing administration techniques obstructing direct visualization of the larynx. The technique described here allows real-time visualization of the rat larynx with concurrent administration of inhaled anesthetic gas. This method is particularly well-suited for recurrent laryngeal nerve or vocal fold pathology studies, where repeat visualization of the larynx is necessary.

Indexed as

Anesthesia, InhalationAnesthetics, InhalationLaryngoscopyAnimalsLarynxMaleRatsRats, Sprague-DawleyAnesthetics, Inhalationanesthesiaendotracheal intubationlaryngoscopyrodentsvocal cords

Identifiers

PMID41334692
PMCPMC12884422

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.