Evidence map›Paper›PMID 41334644›Full record

ArticleActa otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale2025

Italian multicentre study to validate the Swallowing Outcome After Laryngectomy (SOAL) questionnaire.

Pietro De Luca, Arianna Di Stadio, Gerardo Petruzzi, Matteo Fermi, Luca Gazzini, Alberto Vito Marcuzzo, Nicoletta Gardenal, Teodoro Aragona, Francesca Atturo, Luca de Campora and 13 more

Abstract readMulticenter StudyValidation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

23 authors.

Pietro De Luca *Otolaryngology Department, Isola Tiberina-Gemelli Isola Hospital, Rome, Italy.
Arianna Di Stadio *ENT Unit-Department of Mental, Physical Health and Preventive Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.
Gerardo PetruzziDepartment Otolaryngology - Head and Neck Surgery, IRCCS Regina Elena National Cancer Institute, Istituti Fisioterapici Ospitalieri (IFO), Rome, Italy.
Matteo FermiOtolaryngology Department, University of Bologna, Bologna, Italy.
Luca GazziniDepartment of Otorhinolaryngology-Head and Neck Surgery, Hospital of Bolzano (SABES-ASDAA), Bolzano-Bozen, Italy.
Alberto Vito MarcuzzoHead and Neck Department, ENT Clinic, University of Trieste, Trieste, Italy.
Nicoletta GardenalHead and Neck Department, ENT Clinic, University of Trieste, Trieste, Italy.
Teodoro AragonaOtolaryngology Department, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Foggia, Italy.
Francesca AtturoOtolaryngology Department, San Giovanni-Addolorata Hospital, Rome, Italy.
Luca de CamporaOtolaryngology Department, San Giovanni-Addolorata Hospital, Rome, Italy.
Alfonso ScarpaDepartment of Medicine, Surgery and Dentistry, University of Salerno, Salerno, Italy.
Emilio AvalloneOtolaryngology Department, San Pio Hospital, Benevento, Italy.
Arianna CaselliDepartment of Otorhinolaryngology-Head and Neck Surgery, Hospital of Bolzano (SABES-ASDAA), Bolzano-Bozen, Italy.
Maria OliveOtolaryngology Department, University of Bologna, Bologna, Italy.
Francesco Antonio SalzanoDepartment of Medicine, Surgery and Dentistry, University of Salerno, Salerno, Italy.
Giancarlo TirelliHead and Neck Department, ENT Clinic, University of Trieste, Trieste, Italy.
Gabriele MolteniOtolaryngology Department, University of Bologna, Bologna, Italy.
Lazzaro CassanoOtolaryngology Department, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Foggia, Italy.
Luca CalabreseDepartment of Otorhinolaryngology-Head and Neck Surgery, Hospital of Bolzano (SABES-ASDAA), Bolzano-Bozen, Italy.
Raul PelliniDepartment Otolaryngology - Head and Neck Surgery, IRCCS Regina Elena National Cancer Institute, Istituti Fisioterapici Ospitalieri (IFO), Rome, Italy.
Livio PresuttiOtolaryngology Department, University of Bologna, Bologna, Italy.
Marco RadiciOtolaryngology Department, Isola Tiberina-Gemelli Isola Hospital, Rome, Italy.
Angelo CamaioniOtolaryngology Department, San Giovanni-Addolorata Hospital, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To report the data obtained by translating the Swallowing Outcomes After Laryngectomy (SOAL) questionnaire in Italian to validate it and offer a valid tool for Italian-speaking patients and clinicians. Methods: A multicentre case-control study was performed between January 1st 2024 and October 1st 2024. In all, 494 patients consecutively treated for laryngeal squamous cell carcinoma were included in the study (group 1). Healthy controls and patients who underwent radiotherapy (group 2) or chemotherapy (group 3) of the head and neck district were the two control groups. Results: Statistically significant differences were observed comparing SOAL scores among the three groups (ANOVA: p < 0.0001); significant differences were observed between group 1 (mean 0.89 +/- 1.31; 95% CI: 0-3) and group 2 (mean 6.78 +/- 4.59; 95% CI: 1-24) (Bonferroni-Holmes [BH] p < 0.01), and group 1 and group 3 (mean 11 +/- 7.47; 95% CI: 0-38) (BH: p 0 < 0.01). Statistically significant differences in the SOAL scores were also identified between group 2 and 3 (BH: p < 0.01). Conclusions: The SOAL questionnaire may be a useful tool to correctly understand patients' concerns for swallowing to promptly and rapidly manage them and improve patient's quality of life.

Indexed as

Carcinoma, Squamous CellDeglutitionDeglutition DisordersLaryngeal NeoplasmsLaryngectomyAgedCase-Control StudiesFemaleHumansItalyMaleMiddle AgedSurveys and QuestionnairesTreatment Outcomefunctional outcomelaryngeal cancerlaryngectomyswallowing

Identifiers

PMID41334644
PMCPMC12673941

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.