Evidence map›Paper›PMID 41334534›Full record

ArticleEuropean urology open science2026

Oncological Results After Accidental Tumor Incision During Partial Nephrectomy.

Markus Varpela, Sara Tornberg, Harry Nisen, Tuomas Mirtti, Petrus Järvinen

Abstract read
In one paragraph

Article in European urology open science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Markus VarpelaDepartment of Urology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Sara TornbergDepartment of Urology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Harry NisenDepartment of Urology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Tuomas MirttiDepartment of Pathology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Petrus JärvinenDepartment of Urology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and objective: Incising or breaking a tumor during surgery for renal cell carcinoma (RCC) is considered an adverse event. The aim of our study was to examine oncological outcomes for patients with accidental tumor incision (ATI) during partial nephrectomy (PN) for cT1 RCC. Methods: We conducted a retrospective single-center study of patients who underwent open, laparoscopic, or robot-assisted PN for cT1a-b RCC. The cohort was divided into groups with and without ATI during PN. The Kaplan-Meier method and a log-rank test were used to estimate and compare recurrence-free survival (RFS) and cancer-specific survival (CSS) for the two groups. Key findings and limitations: Among 813 patients, ATI was recorded for 103 cases (13%). Disease recurrence during follow-up occurred in 15 patients in the ATI group and 15 in the group without ATI. RFS differed significantly between the groups according to Kaplan-Meier analysis ( Conclusions and clinical implications: Our results demonstrate that ATI during PN is associated with greater risk of disease recurrence in T1 RCC, even though there was no significant difference in CSS over intermediate follow-up. Clinicians should take intraoperative precautions to minimize ATI and consider extended surveillance for patients in whom ATI occurs. Further research is warranted to explore preventative strategies and the long-term impact of ATI on survival. Patient summary: We looked at cancer control outcomes after accidental incision into a tumor (ATI for short) during partial kidney removal for kidney cancer. The rate of cancer recurrence was higher in the group with ATI than in the group without ATI.

Indexed as

Accidental tumor incisionPartial nephrectomyRenal cell carcinoma

Identifiers

PMID41334534
PMCPMC12666582

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