ReviewJugan geon-gang gwa jilbyeong2023
[Adverse Reactions after Smallpox Vaccination and Adverse Reaction Treatment by Vaccinia Immune Globulin].
Review in Jugan geon-gang gwa jilbyeong, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The smallpox vaccine, which is based on vaccinia virus, has been effective in preventing this disease. Since the World Health Organization declared the eradication of smallpox in 1980, there has been no concern about the natural occurrence of smallpox, so vaccinations of the general population is not currently being conducted. However, as the variola virus is a pathogen that is possibly to be used in bioterrorism and is vaccinated against bioterrorism response personnel and people who may be exposed to the virus. These smallpox vaccines can cause local and minor adverse reactions, and in the case of the first and second generation smallpox vaccines, serious life-threatening complications may occur. Accordingly, vaccinia immune globulin (VIG) is used as a treatment for abnormal reactions caused by vaccination of the smallpox. However, since "VIG" is produced using the sera of people vaccinated against smallpox, the effectiveness and production between lots are variable, and demand may exceed supply. To compensate for these shortcomings, research and development of a smallpox vaccine side effect treatment that can be produced in various ways, based on human monoclonal antibodies with neutrality against the vaccinia virus and with standard effectiveness is underway.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.