Activatable self-reporting cyclization reaction for in-cell synthesis of cyclocyanines.

He Hang, Xia Wang, Zhaobin Wang, Chi Meng, Qihang Sun, Ziyue Yang, Fude Feng

Abstract read

In one paragraph

Article in Chemical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

He HangMOE Key Laboratory of High Performance Polymer Materials and Technology, Department of Polymer Science and Engineering, School of Chemistry and Chemical Engineering, Nanjing University Nanjing 210023 P. R. China fengfd@nju.edu.cn.

Xia WangMOE Key Laboratory of High Performance Polymer Materials and Technology, Department of Polymer Science and Engineering, School of Chemistry and Chemical Engineering, Nanjing University Nanjing 210023 P. R. China fengfd@nju.edu.cn.

Zhaobin WangMOE Key Laboratory of High Performance Polymer Materials and Technology, Department of Polymer Science and Engineering, School of Chemistry and Chemical Engineering, Nanjing University Nanjing 210023 P. R. China fengfd@nju.edu.cn.

Chi MengMOE Key Laboratory of High Performance Polymer Materials and Technology, Department of Polymer Science and Engineering, School of Chemistry and Chemical Engineering, Nanjing University Nanjing 210023 P. R. China fengfd@nju.edu.cn.

Qihang SunMOE Key Laboratory of High Performance Polymer Materials and Technology, Department of Polymer Science and Engineering, School of Chemistry and Chemical Engineering, Nanjing University Nanjing 210023 P. R. China fengfd@nju.edu.cn.

Ziyue YangMOE Key Laboratory of High Performance Polymer Materials and Technology, Department of Polymer Science and Engineering, School of Chemistry and Chemical Engineering, Nanjing University Nanjing 210023 P. R. China fengfd@nju.edu.cn.

Fude FengMOE Key Laboratory of High Performance Polymer Materials and Technology, Department of Polymer Science and Engineering, School of Chemistry and Chemical Engineering, Nanjing University Nanjing 210023 P. R. China fengfd@nju.edu.cn.ORCID https://orcid.org/0000-0002-5348-5959

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Generally, fluorescence "turn-on" click reactions require special activation triggers and heavily rely on preformed fluorophores. Herein, we reported an activatable self-reporting click-like reaction for one-pot synthesis of cyclic cyanines (CCClick) by clicking formaldehyde (FA) into dimeric Fischer bases, using biocompatible metal ions or complexes (

Identifiers

PMID41334045

DOI10.1039/d5sc05408g

PMCPMC12666538

What OpenQuestion holds

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LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.