Evidence map›Paper›PMID 41333983›Full record

ArticleERJ open research2025

Home sputum collection for

Gina Hong, Joanna Walsh, Allen Koshy, Jesse Y Hsu, Anna L O'Dea, Elisa M Vesely, Warda Memon, Rebecca H Dezube, Christopher H Goss, Louisa B Goss and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ERJ open research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Gina HongDepartment of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.ORCID https://orcid.org/0000-0001-9321-8399
Joanna WalshDepartment of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Allen KoshyDepartment of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Jesse Y HsuDepartment of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Anna L O'DeaDepartment of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Elisa M VeselyDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, NH, USA.
Warda MemonDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, NH, USA.
Rebecca H DezubeDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID https://orcid.org/0009-0007-2951-3693
Christopher H GossDepartment of Medicine, University of Washington, Seattle, WA, USA.
Louisa B GossPublic Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA.ORCID https://orcid.org/0009-0005-2936-2405
Alicia GreeneDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Jane E GrossDepartments of Pediatrics and Medicine, National Jewish Health, Denver, CO, USA.
Alexandra WilsonDepartments of Pediatrics and Medicine, National Jewish Health, Denver, CO, USA.ORCID https://orcid.org/0000-0001-7157-7462
David P NicholsCystic Fibrosis Foundation, Bethesda, MD, USA.
Sean X ZhangDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Robert A CramerDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, NH, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Elexacaftor/tezacaftor/ivacaftor (ETI) has impacted the ability for people with cystic fibrosis (PwCF) to spontaneously expectorate sputum, leading to lower respiratory sampling rates and infection detection challenges. Home sampling may permit a potential strategy for fungal detection in PwCF. Methods: We conducted a prospective decentralised cohort study of PwCF to test the feasibility of home sputum collection and ambient temperature transport for Results: We enrolled 76 adults with cystic fibrosis (CF) with a median (interquartile range) forced expiratory volume in 1 s (FEV Conclusion: Home sputum collection is feasible in adults with CF.

Identifiers

PMID41333983
PMCPMC12666647

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.