ArticleCureus2025
Association Between Cerebral Blood Flow Velocity and Neurological Outcomes After Cardiac Arrest: A Retrospective Transcranial Color Flow Imaging Study.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionNeurological outcomes after cardiac arrest (CA) remain a challenge in critical care. Time-averaged maximum flow velocity (TAMX) measured via transcranial ultrasound has been suggested as a potential predictor of neurological prognosis, but its relationship remains unclear. This study investigated the association between TAMX, recorded using transcranial color flow imaging (TCCFI), and neurological outcomes.
methodsThis single-center retrospective study included patients admitted to the ICU with initial ventricular fibrillation (VF) following CA. Patients aged <18 years and those who developed cerebral hemorrhage or infarction during their course were excluded. The primary outcome assessed was the cerebral performance category (CPC) at discharge, with CPC 1-2 categorized as 'good CPC.' Logistic regression models were used to analyze the relationship between TAMX and good CPC, adjusting for body temperature, mean arterial pressure, pH, hemoglobin level at examination, and time from CA to examination. The TAMX was categorized into three groups (low, medium, and high), with medium as the reference for subsequent analyses.
resultsAmong 41 patients, TAMX was significantly associated with good CPC in logistic regression analyses. The medium TAMX group showed significantly better neurological outcomes (CPC 1-2, 78.9%) compared with the high TAMX group (30.8%, p = 0.01). In adjusted analyses, the medium TAMX group was significantly associated with favorable CPC outcomes compared with the high group.
conclusionThe TAMX measured via TCCFI may be associated with neurological outcomes in post-CA patients. Medium TAMX levels were associated with better neurological recovery than high levels. The TAMX may serve as a simple bedside prognostic marker, but further studies are warranted to validate these findings and clarify the underlying mechanisms.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.