ArticleCureus2025
Impact of Multiple Viral Detections by FilmArray® on the Severity of Pediatric Respiratory Infections: A Retrospective Single-Center Study.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction FilmArray® Respiratory Panel (FA) is a rapid multiplex polymerase chain reaction (PCR) assay that can detect various viruses. While some studies have indicated that viral co-infections might exacerbate severity, others have found no notable difference when compared to single-virus infections, leaving the overall impact uncertain. Methods We retrospectively reviewed pediatric patients diagnosed with viral respiratory infections who underwent FA testing at the Teikyo University Hospital between April 2020 and March 2025. Only cases of viral detection were included. FA detects pathogens, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), human metapneumovirus (hMPV), human rhinovirus/enterovirus, influenza A and B viruses, human parainfluenza virus type 1-4, respiratory syncytial virus (RSV), common coronaviruses, and adenovirus. Clinical severity indicators were compared between the single- and multiple-virus groups using multivariate regression. Patients with
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