Evidence map›Paper›PMID 41333918›Full record

ArticleMediators of inflammation2025

The Impact of the hsCRP/BMI Ratio on Cardiovascular Outcomes in CAD Patients: A Population-Based Study.

Da Liu, Xuliang Wang, Kuo Zhang, Xiangbin Meng, Jingjia Wang, Jie Yang, Jun Gao, Yuangengshuo Wang, Jun Wen, Chen Li and 6 more

Abstract read
In one paragraph

Article in Mediators of inflammation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Da LiuThe Second Affiliated Hospital, Southern University of Science and Technology, Shenzhen 518055, China.ORCID https://orcid.org/0000-0001-5091-0545
Xuliang WangState Key Laboratory of Vascular Homeostasis and Remodelling, NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Beijing Key Laboratory of Cardiovascular Receptors Research, Department of Cardiology, Institute of Vascular Medicine, Peking University Third Hospital, Peking University, Beijing 100191, China.ORCID https://orcid.org/0000-0001-6520-6948
Kuo ZhangState Key Laboratory of Cardiovascular Disease, Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.ORCID https://orcid.org/0000-0001-8152-0750
Xiangbin MengThe Second Affiliated Hospital, Southern University of Science and Technology, Shenzhen 518055, China.ORCID https://orcid.org/0000-0002-4252-7869
Jingjia WangState Key Laboratory of Vascular Homeostasis and Remodelling, NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Beijing Key Laboratory of Cardiovascular Receptors Research, Department of Cardiology, Institute of Vascular Medicine, Peking University Third Hospital, Peking University, Beijing 100191, China.ORCID https://orcid.org/0000-0003-1556-9315
Jie YangState Key Laboratory of Vascular Homeostasis and Remodelling, NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Beijing Key Laboratory of Cardiovascular Receptors Research, Department of Cardiology, Institute of Vascular Medicine, Peking University Third Hospital, Peking University, Beijing 100191, China.ORCID https://orcid.org/0000-0002-3810-2542
Jun GaoState Key Laboratory of Vascular Homeostasis and Remodelling, NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Beijing Key Laboratory of Cardiovascular Receptors Research, Department of Cardiology, Institute of Vascular Medicine, Peking University Third Hospital, Peking University, Beijing 100191, China.ORCID https://orcid.org/0000-0002-8599-4969
Yuangengshuo WangState Key Laboratory of Vascular Homeostasis and Remodelling, NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Beijing Key Laboratory of Cardiovascular Receptors Research, Department of Cardiology, Institute of Vascular Medicine, Peking University Third Hospital, Peking University, Beijing 100191, China.ORCID https://orcid.org/0009-0008-9709-9954
Jun WenState Key Laboratory of Vascular Homeostasis and Remodelling, NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Beijing Key Laboratory of Cardiovascular Receptors Research, Department of Cardiology, Institute of Vascular Medicine, Peking University Third Hospital, Peking University, Beijing 100191, China.ORCID https://orcid.org/0000-0003-0861-5803
Chen LiState Key Laboratory of Vascular Homeostasis and Remodelling, NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Beijing Key Laboratory of Cardiovascular Receptors Research, Department of Cardiology, Institute of Vascular Medicine, Peking University Third Hospital, Peking University, Beijing 100191, China.ORCID https://orcid.org/0009-0008-8789-3759
Mingqi ZhengDepartment of Cardiology, The First Hospital of Hebei Medical University, No. 89 Donggang Road, Shijiazhuang, Hebei 050000, China.ORCID https://orcid.org/0000-0002-4300-0209
Gang LiuDepartment of Cardiology, The First Hospital of Hebei Medical University, No. 89 Donggang Road, Shijiazhuang, Hebei 050000, China.ORCID https://orcid.org/0000-0003-1221-3698
Yue MaState Key Laboratory of Vascular Homeostasis and Remodelling, NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Beijing Key Laboratory of Cardiovascular Receptors Research, Department of Cardiology, Institute of Vascular Medicine, Peking University Third Hospital, Peking University, Beijing 100191, China.ORCID https://orcid.org/0000-0003-4418-5249
Wenyao WangState Key Laboratory of Vascular Homeostasis and Remodelling, NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Beijing Key Laboratory of Cardiovascular Receptors Research, Department of Cardiology, Institute of Vascular Medicine, Peking University Third Hospital, Peking University, Beijing 100191, China.ORCID https://orcid.org/0000-0002-1296-9324
Yi-Da TangDepartment of Cardiology, The First Hospital of Hebei Medical University, No. 89 Donggang Road, Shijiazhuang, Hebei 050000, China.ORCID https://orcid.org/0000-0003-2716-9917
Chunli ShaoState Key Laboratory of Vascular Homeostasis and Remodelling, NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Beijing Key Laboratory of Cardiovascular Receptors Research, Department of Cardiology, Institute of Vascular Medicine, Peking University Third Hospital, Peking University, Beijing 100191, China.ORCID https://orcid.org/0000-0001-6366-1285

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: It remains uncertain whether a novel composite indicator, the high sensitivity C-reactive protein (CRP) (hsCRP)-to-body mass index (BMI) ratio (CBR), is associated with unfavourable events in subjects who have undergone drug-eluting stent (DES) implantation. Therefore, we conducted a prospective cohort study to evaluate the associations between the CBR and adverse outcome occurrences. Methods: From January 2013 to December 2013, a total of 9810 subjects who underwent DES implantation were enrolled in the study. The participants were divided into three groups on the basis of the CBR. We defined the primary endpoint as the occurrence of major adverse cardiovascular and cerebrovascular events (MACCEs), and the secondary endpoints included the occurrence of all-cause death, myocardial infarction(MI), stroke or target vessel revascularization (TVR). Kaplan‒Meier (K‒M) analysis and Cox regression analysis were performed to assess the discrepancy in the risk of adverse outcomes between the different CBR groups. Results: Over an average follow-up period of 26.7 months, 1022 MACCEs were recorded, which included 122 deaths, 392 MIs, 156 strokes and 461 instances of TVR. The results from the K‒M analysis suggested that the rates of MACCEs and MI increased with increasing tertiles of the CBR. Furthermore, Cox regression analysis demonstrated that there were significant associations between a high CBR and increased MACCE and MI risk. Conclusion: In subjects who underwent DES implantation, a higher CBR was significantly related to increased long-term MACCE and MI risk.

Indexed as

Body Mass IndexCardiovascular DiseasesCoronary Artery DiseaseC-Reactive ProteinAgedDrug-Eluting StentsFemaleHumansKaplan-Meier EstimateMaleMiddle AgedMyocardial InfarctionProportional Hazards ModelsProspective StudiesRisk FactorsStrokeC-Reactive ProteinBMICADDEShigh-sensitivity C-reactive proteininflammation

Identifiers

PMID41333918
PMCPMC12668850

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.