ArticleFrontiers in medicine2025
Association between ABO blood group system and autoimmune liver disease.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Cytokine Gene Polymorphisms Modulate Isohemagglutinin Titers and Classes: Another Aspect Towards the Link Between ABO Groups and Human Pathologies?International journal of molecular sciences · 2026Article
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Authors and funding
3 authors.
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Abstract
Background: Autoimmune liver disease (AILD) is a chronic inflammatory liver disease mediated by abnormal autoimmune response, and its pathogenesis has not been fully elucidated. Studies have shown that ABO blood is associated with autoimmune diseases, but the relationship between ABO blood groups and AILD has not been studied. The purpose of this study is to examine whether there is a correlation between ABO blood group and AILD. Methods: A retrospective cohort study was conducted on 114 AILD patients and 1,167 healthy individuals from January 2019 to February 2024. Blood type was determined with the gel microcolumn assay. Chi-square test and logistic regression were performed to investigate the association between blood type and the risk of AILD. Results: Of 114 patients, 44 (38.60%) were diagnosed with autoimmune hepatitis (AIH), and 70 (61.40%) were diagnosed with primary biliary cholangitis (PBC). A significant difference was found between ABO blood groups and AILD patients. Compared with the controls, blood type A was more prevalent in the AILD group (OR, 1.784; Conclusion: Our findings suggest that ABO blood groups could potentially affect the presence of AILD.
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