Evidence map›Paper›PMID 41333614›Full record

ArticleEuropean clinical respiratory journal2025

First report of bilateral Bronchial Rheoplasty for treating chronic bronchitis performed in a single procedure.

Kristine Jensen, Erik L Secher, Regitze H Libermann, William S Krimsky, Michael Perch

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In one paragraph

Article in European clinical respiratory journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kristine JensenDepartment of Cardiology, Section for Lung Transplantation and Respiratory Medicine, Rigshospitalet, Copenhagen, Denmark.
Erik L SecherDepartment of Cardiothoracic Anaesthesia Heartcenter, Rigshospitalet, Copenhagen, Denmark.
Regitze H LibermannDepartment of Cardiology, Section for Lung Transplantation and Respiratory Medicine, Rigshospitalet, Copenhagen, Denmark.
William S KrimskyGalvanize Therapeutics, Redwood City, CA, USA.
Michael PerchDepartment of Cardiology, Section for Lung Transplantation and Respiratory Medicine, Rigshospitalet, Copenhagen, Denmark.ORCID https://orcid.org/0000-0001-9740-1246

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The RheOx system delivers brief, high-voltage electrical pulses to the airway lining, promoting the regeneration of healthy tissue and reducing mucus production in COPD patients with chronic bronchitis. The procedure, called Rheoplasty, is performed under general anesthesia using a bronchoscope with a 2.8-mm working channel. Initially, we conduct Bilateral Bronchial Rheoplasty in stages, spaced approximately one month apart, to allow patients to recover and minimize risks. Recent studies have not reported any device-related Serious Adverse Events (SAEs) with Rheoplasty, but some procedure-related SAEs occurred within six months, in-cluding COPD exacerbation in 13.3% of cases and one instance of atrial fibrillation. Case: We present the first case of simultaneous bilateral Bronchial Rheoplasty, treating both lungs during one procedure. Contrary to expectations, this did not increase complications in our patient. Consolidating the procedure into one session may reduce risks, patient discomfort, and costs, although further research is needed to confirm these benefits.

Indexed as

bronchitisCOPDcoughinterventional pulmonologyrheoplasty

Identifiers

PMID41333614
PMCPMC12667332

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.