Evidence map›Paper›PMID 41333610›Full record

ArticleTransboundary and emerging diseases2025

Development and Comparison of Indirect ELISAs for Detecting IgG and IgA Antibodies Against Major Structural Proteins of Porcine Deltacoronavirus With Virus Neutralization as a Benchmark.

Dexin Li, Junhua Deng, Yunjing Zhang, Zenglin Wang, Yufang Li, Liying Hao, Kegong Tian, Xiangdong Li

Abstract readComparative Study
In one paragraph

Article in Transboundary and emerging diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dexin LiJiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Junhua DengLuoyang Putai Biotechnology Co. Ltd., Luoyang, China.
Yunjing ZhangNational Research Center for Veterinary Medicine, Luoyang, China.
Zenglin WangJiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Yufang LiLuoyang Putai Biotechnology Co. Ltd., Luoyang, China.
Liying HaoLuoyang Putai Biotechnology Co. Ltd., Luoyang, China.
Kegong TianNational Research Center for Veterinary Medicine, Luoyang, China.ORCID https://orcid.org/0000-0001-5362-1415
Xiangdong LiJiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University, Yangzhou, China.ORCID https://orcid.org/0000-0002-4635-1602

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Porcine deltacoronavirus (PDCoV) is an emerging enteric pathogen that causes substantial economic losses in the global swine industry. Although neutralizing antibodies (NAbs) are a key indicator of vaccine efficacy, their diagnostic concordance with IgG/IgA levels measured by indirect enzyme-linked immunosorbent assays (iELISAs) targeting major structural proteins has not been systematically evaluated. In this study, the full-length spike (S), S1 domain, and receptor-binding domains (RBD) from a highly virulent PDCoV strain were expressed in CHO cells. At the same time, the membrane (M) and nucleocapsid (N) proteins were produced in

Indexed as

Antibodies, ViralCoronavirus InfectionsDeltacoronavirusImmunoglobulin AImmunoglobulin GSwine DiseasesViral Structural ProteinsAnimalsAntibodies, NeutralizingCHO CellsCricetulusEnzyme-Linked Immunosorbent AssayNeutralization TestsSwineAntibodies, NeutralizingAntibodies, ViralImmunoglobulin AImmunoglobulin GViral Structural ProteinsIgAIgGindirect ELISAneutralizing antibodiesporcine deltacoronavirus

Identifiers

PMID41333610
PMCPMC12668856

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.