ArticleFrontiers in neuroscience2025
Effects of a pain oriented biobehavioral therapeutic education program on brain plasticity and pain intensity in subjects with chronic musculoskeletal pain: a feasibility study of a randomized controlled trial.
Article in Frontiers in neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Article
Corrections and comments
- Erratum issued
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Chronic pain significantly impacts the physical, emotional, and social wellbeing of individuals. Despite advances in treatments, chronic pain prevalence continues to rise, emphasizing the need for comprehensive therapeutic approaches. Objective: This study aimed to evaluate the feasibility and preliminary effects of a one-month Pain Oriented Biobehavioral Therapeutic Education (POBTE) program on clinical outcomes for chronic primary musculoskeletal pain. Methods: In a single-blind feasibility pilot of a randomized controlled trial, 16 participants were assigned to an intervention group receiving POBTE education and exercise ( Results: The intervention group showed a significant increase in BDNF levels from a mean of 2.174 at baseline to 3.063 at the end of treatment ( Conclusion: The POBTE program appears feasible and acceptable, showing preliminary signals consistent with potential improvements in several clinical variables related to chronic pain management. These exploratory findings support the need for larger-scale, adequately powered trials.
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