Evidence map›Paper›PMID 41332979›Full record

ArticleInternational journal of microbiology2025

Prevalence, Antimicrobial Resistance, and Risk Factors of Enteric Bacterial Infections Among Children Under Five in Nairobi County, Kenya.

Davis Kimile, Perpetual Ndung'u, Peter Karanja, Gervason Moriasi

Abstract read
In one paragraph

Article in International journal of microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Davis KimileDepartment of Medical Laboratory Sciences, School of Biomedical Sciences, Jomo Kenyatta University of Agriculture and Technology, Nairobi, Kenya.ORCID https://orcid.org/0009-0001-7967-271X
Perpetual Ndung'uDepartment of Medical Laboratory Sciences, School of Biomedical Sciences, Jomo Kenyatta University of Agriculture and Technology, Nairobi, Kenya.
Peter KaranjaDepartment of Medical Laboratory Sciences, School of Biomedical Sciences, Jomo Kenyatta University of Agriculture and Technology, Nairobi, Kenya.
Gervason MoriasiDepartment of Biochemistry, Microbiology, and Biotechnology, School of Pure and Applied Sciences, Kenyatta University, Nairobi, Kenya.ORCID https://orcid.org/0000-0001-5604-9987

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Diarrheal disease remains a major cause of morbidity and mortality in children under 5 years, with the highest burden in sub-Saharan Africa. This study investigated the bacterial etiology, antimicrobial resistance (AMR), and risk factors in childhood diarrhea in Nairobi, Kenya. Methods: A cross-sectional study was conducted among 216 children aged 0-60 months presenting with diarrhea at hospitals in Nairobi County. Stool samples were cultured and isolates tested against eight antibiotics. Caregiver questionnaires assessed risk factors. Associations were evaluated using Fisher's exact test and odds ratios (ORs) were calculated to determine effect sizes. Results: A total of 204 bacterial isolates were recovered. Conclusion: Childhood diarrhea in Nairobi is predominantly bacterial, driven by diverse pathogens and exacerbated by poor hygiene and alarmingly high AMR. Urgent integrated interventions are needed, including strengthening WASH infrastructure, promoting rational antibiotic use, and enhancing AMR surveillance. These findings provide a critical baseline for public health action and underscore the need to safeguard last-line antibiotics.

Indexed as

antimicrobial resistance (AMR)children under fiveenteric bacterial infectionsmultidrug resistance (MDR)water, sanitation, and hygiene (WASH)

Identifiers

PMID41332979
PMCPMC12668859

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.