ReviewMaterials today. Bio2025
Materiobiology in the omics era.
Review in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Targeting the osteoporotic bone microenvironment: Mechanistic insight and therapeutic biomaterials for accelerating bone regeneration.Bioactive materials · 2026Review
- Hydrogels for Bone Repair: Construction Strategies and Applications.Smart medicine · 2026Review
- Mechanism-guided biomaterial strategies for intervertebral disc degeneration: Pathological heterogeneity, functional classification, and translational perspectives.Journal of tissue engineeringReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Omics technologies can uncover the complex regulatory mechanisms of living systems at multiple levels, including genes, transcripts, proteins, metabolites and immune networks. They also provide an integrative framework to study how cells interact with their environment. In materiobiology, cellular responses to materials involve diverse processes. This review summarizes the applications of single-cell transcriptomics, transcriptomics, RNomics, genomics, proteomics, metabolomics, lipidomics, glycomics and immunomics in materiobiology. We highlight how these approaches reveal cell heterogeneity, transcriptional and epigenetic regulation, genetic determinants, protein and metabolic pathways, lipid and glycan remodeling and immune networks in the context of biomaterial interactions. In addition, we discuss how multi-omics strategies support the construction of bone organoids, which serve as physiologically relevant models to investigate bone development, disease mechanisms and material-driven repair. Together, these advances provide a theoretical foundation and methodology for the rational design of next-generation biomaterials with improved functionality and precision in regenerative medicine. This review outlines how multi-omics technologies drive materiobiology, bridging molecular insights with material innovation for precision and regenerative medicine.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.