SynthesisFrontiers in pediatrics2025
Hematological parameters of bronchopulmonary dysplasia in preterm infants: a meta-analysis.
Synthesis in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Bronchopulmonary dysplasia (BPD) represents the most widespread and severe form of chronic pulmonary disease in preterm infants. Studies have revealed an association between BPD and hematological parameters (HPs); however, the findings are inconsistent. Objectives: This study utilized a systematic review and meta-analysis to summarize the association. Methods: The Web of Science, Cochrane Library, Embase, and PubMed were retrieved up to May 4, 2024, with an update on April 10, 2025. Studies investigating the correlation between HPs and BPD in preterm infants were included. This study adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The quality of the studies was evaluated via the Newcastle-Ottawa Scale. Stata 18 and MetaDisc were utilized for statistical analysis. Results: This meta-analysis encompassed 20 studies with a total of 4,752 participants and investigated the association between HPs and BPD in neonates. Statistically significant differences were found between BPD and non-BPD infants for eight parameters: neutrophil ( Conclusions: The current study indicated significant differences in NEU, HGB, HCT, RBC, PLT, NLR, and SIRI between BPD and non-BPD patients, with elevated NEU, NLR, and SIRI and reduced HGB, HCT, RBC, and PLT. However, this study had its limitations. Further analysis requires more multicenter, large-sample prospective studies. Systematic Review Registration: https://www.crd.york.ac.uk/PROSPERO/, identifier CRD42024552716.
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