Evidence map›Paper›PMID 41332867›Full record

ArticlemedRxiv : the preprint server for health sciences2025

Quantifying Sleep-Wake Rhythms in the Hospital Environment with Digital Technologies.

Carsten Skarke, Nadim El Jamal, Michael V Genuardi, Thomas G Brooks, Antonijo Mrčela, Nicholas F Lahens, Makayla Cordoza, Sean Sarles, Amarachi Mbadugha, Dineth R Karunamuni and 12 more

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

22 authors.

Carsten SkarkeInstitute for Translational Medicine and Therapeutics (ITMAT), University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.ORCID 0000-0001-5145-3681
Nadim El JamalInstitute for Translational Medicine and Therapeutics (ITMAT), University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
Michael V GenuardiDepartment of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
Thomas G BrooksInstitute for Translational Medicine and Therapeutics (ITMAT), University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.ORCID 0000-0002-6980-0079
Antonijo MrčelaInstitute for Translational Medicine and Therapeutics (ITMAT), University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
Nicholas F LahensInstitute for Translational Medicine and Therapeutics (ITMAT), University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
Makayla CordozaSchool of Nursing, Vanderbilt University, Nashville, TN 37240, USA.
Sean SarlesDepartment of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
Amarachi MbadughaInstitute for Translational Medicine and Therapeutics (ITMAT), University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
Dineth R KarunamuniDepartment of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
Shikhar GuptaDepartment of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
Charles J BaeDepartment of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
Amita SehgalDepartment of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
Thomas P CappolaDepartment of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
Jacob T GutscheDepartment of Anesthesiology and Critical Care, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
Pavan AtluriDepartment of Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
Nimesh D DesaiDepartment of Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
Michael A AckerDepartment of Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
Gregory R GrantInstitute for Translational Medicine and Therapeutics (ITMAT), University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
Richard J SchwabDepartment of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
Ilene M RosenDepartment of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
Garret A FitzGeraldInstitute for Translational Medicine and Therapeutics (ITMAT), University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.

Funding

Phenotypic Diversity in COVID-19UL1TR001878 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2016 to 2025
$102.4M
Evaluating the Role of Sleep in the Development of Intensive Care Unit DeliriumR00NR019862 · NINR · VANDERBILT UNIVERSITY · PI CORDOZA, MAKAYLA · 2023 to 2025
$731k
NCATS NIH HHS UL1 TR001878NINR NIH HHS R00 NR019862
6 · The paper itself

Abstract

Postoperative clinical care is prone to circadian desynchronization that, in turn, may influence health outcomes. We collected 1.8 million data points using 11 remote sensors during preoperative, in-hospital and post-discharge settings in 13 elective cardiac surgery patients. We found that room traffic continued during nighttime with ≥1 visit/h. Sound levels exceeded the recommended 45 dBA threshold (51.9±3.3 versus 48.3±4.2 dBA during nighttime). Brightness dropped at night (89.9±87.7 to 3.7±9.8 lux), but bright light exposures occurred. Ambient room temperature lacked sleep-inducing diurnal variability. Behavioral-physiological rhythms were disrupted (decreased amplitude of heart rate variability;

Identifiers

PMID41332867
PMCPMC12668063

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.