Evidence map›Paper›PMID 41332780›Full record

ArticlebioRxiv : the preprint server for biology2025

An integrative computational approach for obstacle avoidance during action selection.

Shan Zhong, Nader Pouratian, Paul Schrater, Vassilios Christopoulos

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shan ZhongAlfred E.Mann Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, USA.
Nader PouratianDepartment of Neurological Surgery, UT Southwestern Medical Center, Dallas, TX, USA.
Paul SchraterDepartment of Computer Science and Engineering, University of Minnesota, Minneapolis, MN, USA.
Vassilios ChristopoulosAlfred E.Mann Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, USA.ORCID 0000-0002-0541-8700

Funding

Modeling and Mapping Human Action Regulation NetworksU01NS132788 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI Vasileios N Christopoulos, NADER POURATIAN · 2023 to 2026
$3.7M
NINDS NIH HHS U01 NS132788
6 · The paper itself

Abstract

Action selection in cluttered environments, where individuals must simultaneously pursue goals and avoid obstacles, presents a significant challenge for the brain. To understand the underlying mechanisms of action selection in such contexts, we propose a computational model that extends stochastic optimal control theory through a novel framework for obstacle avoidance. The model decomposes action selection as a weighted combination of individual control policies, each generated for either target approach or obstacle avoidance. By integrating value information from goals, obstacles, and actions into a unified measure of "relative desirability", the model dynamically determines the contribution of each policy to the overall action selection process. We evaluated the framework using simulated target-reaching tasks in cluttered environments based on previous human studies. The results showed that the model captures key features of human motor behavior, including the influence of obstacle properties on movement trajectories and the transient tendency to initiate movements toward obstacles before avoidance. This work offers new insights into the dynamic interaction between approach and avoidance behaviors, providing a comprehensive framework for understanding action selection in complex and naturalistic settings.

Identifiers

PMID41332780
PMCPMC12667892

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.