Evidence map›Paper›PMID 41332748›Full record

ArticlebioRxiv : the preprint server for biology2025

Dengue Virus NS1 Binds Ephrin B1 to Trigger Endothelial Dysfunction.

Felix Pahmeier, Sabrina R Hammond, Charlotte Flory, Xinyi Feng, Saeyoung E Lee, Erika V Jimenez-Posada, Elias M Duarte, Jaime A Cardona-Ospina, Aquena H Ball, Nharae E Lee and 6 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Felix PahmeierDivision of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA.ORCID 0000-0002-7445-2259
Sabrina R HammondDivision of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA.
Charlotte FlorySystems Arbovirology, Leibniz Institute of Virology, Hamburg, Germany.ORCID 0000-0001-5049-6380
Xinyi FengDivision of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA.
Saeyoung E LeeDivision of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA.ORCID 0009-0004-0662-5607
Erika V Jimenez-PosadaDivision of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA.ORCID 0000-0002-3737-9427
Elias M DuarteDivision of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA.
Jaime A Cardona-OspinaDivision of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA.ORCID 0000-0003-3996-2293
Aquena H BallDivision of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA.ORCID 0009-0002-7193-5738
Nharae E LeeDivision of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA.
Kayla LeungDivision of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA.
Laurentia V TjangDivision of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA.ORCID 0000-0003-0949-3713
P Robert BeattyDivision of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA.ORCID 0000-0003-1645-2880
Scott B BieringDivision of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA.ORCID 0000-0003-1991-629X
Pietro ScaturroSystems Arbovirology, Leibniz Institute of Virology, Hamburg, Germany.ORCID 0000-0001-9098-3087
Eva HarrisDivision of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA.ORCID 0000-0002-7238-4037

Funding

Research Project 4: Mining human antibody responses to inform vaccine and therapeutic designU19AI181977 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI Jesse Hong-Sae Erasmus · 2024 to 2026
$56.1M
Host factors and viral determinants mediating flavivirus NS1 tissue-specific endothelial dysfunction and vascular leakR01AI168003 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI Eva Harris · 2022 to 2026
$3.2M
NIAID NIH HHS R01 AI168003NIAID NIH HHS U19 AI181977
6 · The paper itself

Abstract

Dengue virus (DENV), a member of the

Identifiers

PMID41332748
PMCPMC12668011

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.