ArticlebioRxiv : the preprint server for biology2025
Elevated synaptic PKA activity and abnormal striatal dopamine signaling in
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Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
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Authors and funding
36 authors.
Bryan J SongThe Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID 0000-0003-0549-4823
Yang GeThe Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID 0000-0003-3139-9053
Ally NicolellaThe Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID 0000-0002-2175-6312
Min Jee KwonThe Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Bart LodderDepartment of Neurobiology, Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA.
Kevin BonannoThe Proteomics Platform, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID 0000-0002-6712-9277
Antia Valle-TojeiroThe Proteomics Platform, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Nolan D HartleyThe Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Kira Perzel MandellThe Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID 0000-0001-6262-6904
John AdeleyeThe Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Deeksha MisriThe Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Chuhan GengThe Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Sahana NatarajanThe Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Inès PicardThe Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Nate ShepardThe Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID 0000-0002-8629-3152
Alyssa HallThe Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Jiawen TianThe Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Sameer AryalThe Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID 0000-0003-3577-4383
Zohreh FarsiThe Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID 0000-0001-7274-981X
Xiao-Man LiuThe Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID 0000-0001-9968-3988
Nader MorshedThe Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID 0000-0002-0346-9651
Naeem M NadafThe Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID 0000-0002-7805-8523
Horia PribiagThe Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID 0000-0001-8455-1966
Sean K SimmonsThe Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID 0000-0002-1537-4000
D R ManiThe Proteomics Platform, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Beth StevensThe Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID 0000-0003-4226-1201
Prabhat S KunwarThe Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Zhanyan FuThe Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Evan Z MacoskoThe Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID 0000-0002-2794-5165
Joshua Z LevinThe Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID 0000-0002-0170-3598
Bernardo L SabatiniDepartment of Neurobiology, Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-0095-9177
Steven A CarrThe Proteomics Platform, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID 0000-0002-7203-4299
Borislav DejanovicThe Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID 0000-0003-4191-5808
Hasmik KeshishianThe Proteomics Platform, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID 0000-0002-0062-9867
Adam J GrangerThe Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID 0000-0002-3953-6764
Morgan ShengThe Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID 0000-0002-8703-5366
Funding
Genetic Analysis and Manipulation Core (GAEC)P50HD105351 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI SCOTT Loren POMEROY, MUSTAFA SAHIN · 2021 to 2026
$9.4MNICHD NIH HHS P50 HD105351
Abstract
Loss-of-function mutations in
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.